• measure Zygosity (DNA)

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YS_3 YS_5 YS_7 YS_10 YS_12 YS_DHBQ14 YS_DHBQ16 YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF1 YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18 YS_TRIP age 1-2 YS_TRIP age 3 YS_TRIP age 4 YS_TRIP age 5 YS_TRIP age 7 YS_TRIP age 10 YS_TRIP age 12
     
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    years
    Zygosity typing based on micro-satellite markers, single nucleotide polymorphisms (SNP), or variable number (short) tandem repeats (VNTRs).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Blood sugar markers

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
    0
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    10
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    30
    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Dipstick

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
    0
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    30
    years
    Urinary dipstick (Siemens, Marburg, Germany) was applied to the first thaw of the urine samples either by dipping in the residual urine volume after aliquoting or by dropping urine on the dipstick to screen for signs of infections in the urine and to measure leukocytes, nitrite, proteins, glucose, and blood presence in the urine.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Inflammation markers

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
    0
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    10
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    20
    25
    30
    years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Oxidative stress markers

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
    0
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    10
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    20
    25
    30
    years
    Oxidative stress markers, including Oxidized DNA/RNA, Total Antioxidant Capacity, and Thiobarbituric acid reactive substances (malondialdehyde), were measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Viral infections

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
    0
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    10
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    20
    25
    30
    years
    Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Urine sample

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YE_COG18
     
    0
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    30
    years
    First-morning, spot, or 24 hour urine sample.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Anthropometry

    Study:Netherlands Twin Register
    Mode of collection: SelfAdministeredQuestionnaire
    Available measurements:
    Young Netherlands Twin Register  YS_1 YS_2 YS_3 YS_5 YS_7 YS_10 YS_12 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18 YS_TRIP age 1 YS_TRIP age 2 YS_TRIP age 1-2 YS_TRIP age 3 YS_TRIP age 4 YS_TRIP age 5 YS_TRIP age 7 YS_TRIP age 10 YS_TRIP age 12
     
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    years
    Anthropometric measurements include height, weight, body mass index (BMI), and body circumferences.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Pubertal Development

    Study:Netherlands Twin Register
    Mode of collection: SelfAdministeredQuestionnaire
    Available measurements:
    Young Netherlands Twin Register  YS_1 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YC_ADHMRI YE_COG18 YS_TRIP age 1-2
     
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    years
    Pubertal Development was assessed through questions about breast growth, menstruation, shaving, deepening of the voice, and growth spurts.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Stop-signal anticipation task - functional MRI

    Study:YOUth
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Child and Adolescent  9 years 12 years
     
    0
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    years
    Stop-signal anticipation task - functional MRI consists of a functional Magnetic Resonance Imaging (fMRI) scan that was acquired while subjects performed the Stop-signal anticipation (inhibition) experiment. The task aims to measure performance and brain activity during actual stopping as well as during the anticipation of stopping. Trials begin with the...
    Created June 5, 2024 • Updated June 20, 2024

  • measure Hair sample

    Study:YOUth
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Baby and Child  30 weeks 10 months 3 years 6 years

    Child and Adolescent  9 years 12 years
     
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    years
    A hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Pubertal Development Scale (PDS)

    Study:YOUth
    Mode of collection: SelfAdministeredQuestionnaire
    Available measurements:
    Child and Adolescent  9 years 12 years
     
    0
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    30
    years
    The Pubertal Development Scale (PDS) assesses the development of secondary sexual characteristics, such as growth spurts, body hair growth, skin changes, breast development and menarche in girls, and voice changes and growth of testes in boys.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Resting state functional Magnetic Resonance Imaging (rsfMRI)

    Study:YOUth
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Baby and Child  0 months

    Child and Adolescent  9 years 12 years
     
    0
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    30
    years
    Functional magnetic resonance imaging (MRI) is a non-invasive technique for examining brain activity. Resting state fMRI aims to assess spontaneous brain activity using MRI while the participant is at rest, not performing any specific task. It captures ongoing functional connectivity patterns within the brain.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Diffusion Tensor Imaging (DTI)

    Study:YOUth
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Baby and Child  0 months

    Child and Adolescent  9 years 12 years
     
    0
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    30
    years
    Diffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Length, weight, head circumference

    Study:YOUth
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Baby and Child  3 years 6 years

    Child and Adolescent  9 years 12 years
     
    0
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    30
    years
    The body measures height, head circumference, and weight were measured by the experimenter in centimeters and kilos respectively. Participants were asked to take off any shoes and large vests and sweaters that could affect these measures.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Stop-signal anticipation task

    Study:YOUth
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Child and Adolescent  9 years 12 years
     
    0
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    25
    30
    years
    The Stop-signal anticipation task aims to measure performance during actual stopping as well as during the anticipation of stopping. Trials begin with the presentation of a cue (0, * or **), representing the stop-signal probability (0, 22 and 33% respectively). Permanently visible are three horizontal white lines, and the goal is to stop a rising bar as...
    Created June 5, 2024 • Updated June 20, 2024

  • measure Emotion experiment

    Study:YOUth
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Child and Adolescent  9 years 12 years
     
    0
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    years
    The Emotion experiment is a task that aims to measure emotional face processing. In the task, participants view pictures of faces (happy, fearful, or neutral), and houses in a pseudorandom order. The stimuli were taken from the Radboud Faces Database (Langner et al., 2010) and are presented in blocks of 18 seconds, with four blocks for each of the four...
    Created June 5, 2024 • Updated June 20, 2024

  • measure Buccal swab

    Study:YOUth
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Baby and Child  20 weeks 5 months 10 months 3 years 6 years

    Child and Adolescent  9 years 12 years
     
    0
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    30
    years
    Buccal swabs are collections of buccal cell scrapings obtained by rubbing buds along the inside of the mouth.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Blood sample

    Study:YOUth
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Baby and Child  20 weeks

    Child and Adolescent  9 years 12 years
     
    0
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    30
    years
    A blood sample consists of taking an amount of a person's blood from their body.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Saliva sample

    Study:YOUth
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Child and Adolescent  9 years 12 years
     
    0
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    30
    years
    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created June 5, 2024 • Updated June 20, 2024
You can also access this registry using the API (see API Docs).