• measure Genotyping array and DNA exome array

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy Birth
     
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    Assessment of single nucleotide polymorphisms (SNPs) as obtained through genotyping arrays.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Skinfold thickness, waist and hip circumference

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  6 weeks 6 months 1 year 2 years 3 years 4 years
     
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    Skinfold thickness, waist and hip circumference were assessed as an indication of body fat. Skinfold thickness can noninvasively and reliably be measured at various sites of the body using a skinfold caliper. Based on measurements at multiple sites of the body, the total body fat and contribution of fat to the body mass can be estimated.
    Created June 5, 2024 • Updated September 19, 2024

  • measure LC-MS lipids

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 9-10 years
     
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    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Genotyping (array)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
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    years
    Assessment of micro-satellite markers, single nucleotide polymorphisms (SNP), and variable number (short) tandem repeats (VNTRs) as obtained through genotyping arrays.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Urine sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 years
     
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    First-morning, spot, or 24 hour urine sample.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Cordblood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
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    A cordblood sample consists of taking an amount of a person's blood from their umbilical cord. The umbilical cord is the rope-like structure that connects a mother to her unborn baby. After the cord is cut, a health care provider will use a tool called a clamp to stop the cord from bleeding. The provider will then use a needle to withdraw blood from the...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Gangliothalamic ovoid diameter and ventricular volume

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  6 weeks
     
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    Cranial ultrasound measurements were performed to obtain gangliothalamic ovoid diameter and ventricular volume.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Cardiac and renal structure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  6 weeks 6 months 2 years 9-10 years
     
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    Ultrasound measurements were performed to obtain measures of cardiac and renal structure.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 years
     
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    A blood sample consists of taking an amount of a person's blood from their body.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Neuromotor development

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  6 weeks 3 months 6 months 1 year
     
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    years
    Neuromotor development was assessed using items from the Touwen’s Neurodevelopmental Examination. Children's motor behavior was observed in supine, prone, sitting, standing, and walking positions.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Glucose metabolism

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 5-6 years
     
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    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Gestational age

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy
     
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    Gestational age is an estimation of the duration of pregnancy, either from the first day of the last menstrual period, or through ultrasound measurements, aiding in tracking fetal development.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Height and weight

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    years
    Height and weight were measured without shoes and heavy clothing.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood pressure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    Blood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Nasal and nasalpharyngeal swab

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 years
     
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    Nasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.
    Created June 5, 2024 • Updated September 19, 2024

  • measure LC-MS amino acids and carnitines

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 9-10 years
     
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    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created June 5, 2024 • Updated September 19, 2024

  • measure DNA methylation (candidate genes)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
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    years
    DNA methylation of selected candidate genes, such as Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT).
    Created June 5, 2024 • Updated September 19, 2024

  • measure DNA methylation (array)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
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    30
    years
    Assessment of DNA methylation as obtained through DNA methylation arrays.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Fetal growth parameters

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy
     
    0
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    years
    Fetal growth was assesses via fetal ultrasounds carried out by sonographics during visits to the research center using standardized ultrasound procedures. Fetal growth measures included crown-rump length, head circumference, abdominal circumference, and femur length. Femur length was used as a proxy for fetal length. Estimated fetal weight was calculated...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Placental haeomynamics

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  Mid pregnancy Late pregnancy
     
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    years
    Placental haeomynamics assesses resistance indices of the uterine and umbilical arteries.
    Created June 5, 2024 • Updated September 19, 2024
You can also access this registry using the API (see API Docs).