Dataset

Gangliothalamic ovoid diameter and ventricular volume

Cranial ultrasound measurements were performed to obtain gangliothalamic ovoid diameter and ventricular volume.

These measurements were only performed in a subgroup of participants.

Citation	Loading citation...
Keywords	brain structure neural structure brain volume ventricles basal ganglia neural white matter
Constructs	physiology
Waves	Generation R 6 weeks C 0 months - 5 months From 2002-01-01 to 2006-12-31
Mode of collection	MeasurementsAndTests Echo
Analysis unit	Individual
Instrument name	Gangliothalamic ovoid diameter and ventricular volume
Measure name	Brain structure

Purpose	The purposes of the Generation R study are to (1) describe normal and abnormal growth, development and health from early fetal life to adulthood in a multi-ethnic population; (2) identify (epi-)genetic, biological, social and environmental determinants of this normal and abnormal growth, development and health; and (3) contribute to the development of strategies for optimizing health and healthcare for pregnant women and children.
description
Alternate title	Generation R, Gen-R
Data access information	Data access requests can be directed to the data management team of the Generation R Study (generationr@erasmusmc.nl), which has a protocol for approving data requests. Because of restrictions based on privacy regulations and informed consent of participants, data cannot be made freely available in a public repository. https://generationr.nl/
Publisher	Erasmus MC
Principal investigators	Bierma - Zeinstra, S.M.A. Erasmus MC Bonsel, G.J. Erasmus MC Büller, H.A. Erasmus MC van Duijn, C.M. Erasmus MC Duijts, L. Erasmus MC Felix, J.F. Erasmus MC Franco, O.H. Erasmus MC Franken, I.H.A. Erasmus University Rotterdam Gaillard, R. Erasmus MC van Grieken, A. Erasmus MC van der Heijden, A.J. Erasmus MC Hillegers, M.H.J. Erasmus MC Hofman, A. Erasmus MC van IJzendoorn, M.H. Erasmus University Rotterdam Ikram, M.A. Erasmus MC Jaddoe, V.W.V. Erasmus MC Jansen, P.W. Erasmus MC Jansen, W. Gemeente Rotterdam de Jongste, J.C. Erasmus MC Keizer, R. Erasmus University Rotterdam Klaver, C.C.W. Erasmus MC van Lenthe, F.J. Erasmus MC van der Lugt, A. Erasmus MC Mackenbach, J.P. Erasmus MC Moll, H.A. Erasmus MC Nijsten, T. Erasmus MC Pardo Cortes, L. Erasmus MC Peeters, R.P. Erasmus MC Raat, H. Erasmus MC Reiss, I.K.M. Erasmus MC de Rijke, Y.B. Erasmus MC van Rijn, B.B. Erasmus MC Rings, E.H. Erasmus MC Rivadeneira, F. Erasmus MC van der Schroeff, M.P. Erasmus MC Snijders, R.F.M. Erasmus MC Steegers, E.A.P. Erasmus MC Tiemeier, H. Erasmus MC Uitterlinden, A.G. Erasmus MC Vis, J.Y. Erasmus MC Verhulst, F.C. Erasmus MC Vernooij, M. Erasmus MC Voortman, T. Erasmus MC de Wilde, E.J. GGD Rotterdam-Rijnmond Wildschut, H. Erasmus MC Witteman, J.C.M. Erasmus MC Wolvius, E.B. Erasmus MC van Schaik, R.H.N. Erasmus MC
Cohort study international identifier
Language	NL
Funding information	All funders are listed via the Generation R website Funder identifier https://generationr.nl/algemeen/donateurs/ Funder identifier type url Funder identifier type URI Funder award title Funder award URI
Contact information	Generation R Data Management Erasmus MC generationr@erasmusmc.nl
References	Growth, development and health from early fetal life until young adulthood: the Generation R Study The Generation R Study: Design and cohort profile The Generation R Study Biobank: a resource for epidemiological studies in children and their parents The Generation R Study: design and cohort update until the age of 4 years The Generation R Study: design and cohort update 2010 The Generation R Study: design and cohort update 2012 Pediatric population-based neuroimaging and the Generation R Study: the intersection of developmental neuroscience and epidemiology The Generation R Study: Biobank update 2015 The Generation R Study: design and cohort update 2017
Additional info (URL)
Additional information
Contributors	The Generation R Study Group Erasmus MC
Time method	Longitudinal
Universe	Youth, and their parents, from the general population followed since prenatal life until young adulthood, all born in Rotterdam, the Netherlands.

Alternate title	GenR , Gen-R
Description	The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic pathways leading to normal and abnormal growth, development and health. An important focus of Generation R is to identify early life determinants of common (mostly non-communicable) diseases in adulthood. Pregnant women living in the Rotterdam area, the Netherlands, were included between 2002 and 2006. After birth, the children and their parents have been followed in multiple assessment waves up until young adulthood.
Purpose	The purposes of the Generation R study are to (1) describe normal and abnormal growth, development and health from early fetal life to adulthood in a multi-ethnic population; (2) identify (epi-)genetic, biological, social and environmental determinants of this normal and abnormal growth, development and health; and (3) contribute to the development of strategies for optimizing health and healthcare for pregnant women and children.
Publisher	Erasmus MC
Creators	Bierma - Zeinstra, S.M.A. Erasmus MC Bonsel, G.J. Erasmus MC Büller, H.A. Erasmus MC van Duijn, C.M. Erasmus MC Duijts, L. Erasmus MC Felix, J.F. Erasmus MC Franco, O.H. Erasmus MC Franken, I.H.A. Erasmus University Rotterdam Gaillard, R. Erasmus MC van Grieken, A. Erasmus MC van der Heijden, A.J. Erasmus MC Hillegers, M.H.J. Erasmus MC Hofman, A. Erasmus MC van IJzendoorn, M.H. Erasmus University Rotterdam Ikram, M.A. Erasmus MC Jaddoe, V.W.V. Erasmus MC Jansen, P.W. Erasmus MC Jansen, W. Gemeente Rotterdam de Jongste, J.C. Erasmus MC Keizer, R. Erasmus University Rotterdam Klaver, C.C.W. Erasmus MC van Lenthe, F.J. Erasmus MC van der Lugt, A. Erasmus MC Mackenbach, J.P. Erasmus MC Moll, H.A. Erasmus MC Nijsten, T. Erasmus MC Pardo Cortes, L. Erasmus MC Peeters, R.P. Erasmus MC Raat, H. Erasmus MC Reiss, I.K.M. Erasmus MC de Rijke, Y.B. Erasmus MC van Rijn, B.B. Erasmus MC Rings, E.H. Erasmus MC Rivadeneira, F. Erasmus MC van der Schroeff, M.P. Erasmus MC Snijders, R.F.M. Erasmus MC Steegers, E.A.P. Erasmus MC Tiemeier, H. Erasmus MC Uitterlinden, A.G. Erasmus MC Vis, J.Y. Erasmus MC Verhulst, F.C. Erasmus MC Vernooij, M. Erasmus MC Voortman, T. Erasmus MC de Wilde, E.J. GGD Rotterdam-Rijnmond Wildschut, H. Erasmus MC Witteman, J.C.M. Erasmus MC Wolvius, E.B. Erasmus MC van Schaik, R.H.N. Erasmus MC
Language	NL
Cohort international identifier
Funding information	All funders are listed via the Generation R website Funder identifier https://generationr.nl/algemeen/donateurs/ url Identifier type URI Funder award title Funder award URI
Cohort reference papers
Classification
Contact information
Waves
Contributors	The Generation R Study Group Erasmus MC
References	Growth, development and health from early fetal life until young adulthood: the Generation R Study The Generation R Study: Design and cohort profile The Generation R Study Biobank: a resource for epidemiological studies in children and their parents The Generation R Study: design and cohort update until the age of 4 years The Generation R Study: design and cohort update 2010 The Generation R Study: design and cohort update 2012 Pediatric population-based neuroimaging and the Generation R Study: the intersection of developmental neuroscience and epidemiology The Generation R Study: Biobank update 2015 The Generation R Study: design and cohort update 2017
Country code	NL
Geographic location	3010-3070
Lowest geographic reference	postal code
Highest geographic reference	city
Cohort universe description	Pregnant women living in the Rotterdam area, the Netherlands, were included between 2002 and 2006. After birth, the children and their parents have been followed in multiple assessment waves up until young adulthood.
Analysis unit
Additional info (URL)
Additional information
Time method	Longitudinal.CohortEventBased

Wave alternate title	6 weeks assessment, Focus 6 weeks, 6w
Short description of the wave	The 6 weeks wave consisted of anthropometrics and motor assessments from visits at the research center (Focus cohort) and the baby well clinic around the age of 1 month (mean age: 1.6 months).
Type of StudyUnit
Publisher	Erasmus MC
Creators	Bierma - Zeinstra, S.M.A. Erasmus MC Bonsel, G.J. Erasmus MC Büller, H.A. Erasmus MC van Duijn, C.M. Erasmus MC Duijts, L. Erasmus MC Felix, J.F. Erasmus MC Franco, O.H. Erasmus MC Franken, I.H.A. Erasmus University Rotterdam Gaillard, R. Erasmus MC van Grieken, A. Erasmus MC van der Heijden, A.J. Erasmus MC Hillegers, M.H.J. Erasmus MC Hofman, A. Erasmus MC van IJzendoorn, M.H. Erasmus University Rotterdam Ikram, M.A. Erasmus MC Jaddoe, V.W.V. Erasmus MC Jansen, P.W. Erasmus MC Jansen, W. Gemeente Rotterdam de Jongste, J.C. Erasmus MC Keizer, R. Erasmus University Rotterdam Klaver, C.C.W. Erasmus MC van Lenthe, F.J. Erasmus MC van der Lugt, A. Erasmus MC Mackenbach, J.P. Erasmus MC Moll, H.A. Erasmus MC Nijsten, T. Erasmus MC Pardo Cortes, L. Erasmus MC Peeters, R.P. Erasmus MC Raat, H. Erasmus MC Reiss, I.K.M. Erasmus MC de Rijke, Y.B. Erasmus MC van Rijn, B.B. Erasmus MC Rings, E.H. Erasmus MC Rivadeneira, F. Erasmus MC van der Schroeff, M.P. Erasmus MC Snijders, R.F.M. Erasmus MC Steegers, E.A.P. Erasmus MC Tiemeier, H. Erasmus MC Uitterlinden, A.G. Erasmus MC Vis, J.Y. Erasmus MC Verhulst, F.C. Erasmus MC Vernooij, M. Erasmus MC Voortman, T. Erasmus MC de Wilde, E.J. GGD Rotterdam-Rijnmond Wildschut, H. Erasmus MC Witteman, J.C.M. Erasmus MC Wolvius, E.B. Erasmus MC van Schaik, R.H.N. Erasmus MC
Funding information	Funder identifier url Identifier type URI Funder award title Funder award URI
References
(sub) cohort	Generation R: Generation R
Life stage
Coverage percentage of the measurement for this wave
Start date wave collection	2002-01-01
End date wave collection	2006-12-31
Wave universe description	0 months - 5 months
Stage of measurement
Language	NL
Description of physical data product	Digital files, biological samples
Additional info (URL)
Additional information
Contributors	The Generation R Study Group Erasmus MC

You can also access this dataset using the API (see API Docs).

author	None
author_email	None
creator_user_id	34768773-4537-4d74-8d9d-11e2b32cbbaf
dc_additional_info	These measurements were only performed in a subgroup of participants.
dc_analysis_unit	{Individual}
dc_cohort	GenR
dc_instrument_name	Gangliothalamic ovoid diameter and ventricular volume
dc_measure_name	Brain structure
id	47e4c755-144f-4d7d-9558-799677db21d9
isopen	False
license_title	None
maintainer	None
maintainer_email	None
metadata_created	2024-10-17T12:30:19.436222
metadata_modified	2024-10-20T12:46:56.325203
name	c658dfd693811a2b091e1f7c2a2062bb
notes	Cranial ultrasound measurements were performed to obtain gangliothalamic ovoid diameter and ventricular volume.
num_resources	0
num_tags	0
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owner_org	8dee8702-82b1-4d76-ba66-bdb5f4b47fa4
private	False
state	active
title	Gangliothalamic ovoid diameter and ventricular volume
type	measure
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'cohort_creator_affiliation_identifier_scheme': 'ROR', 'cohort_creator_affiliation_identifier_schemeuri': 'https://ror.org/', 'cohort_creator_identifier_schemeuri': 'https://orcid.org/', 'cohort_creator_identifier_type': 'ORCID', 'cohort_creator_name': 'van Schaik, R.H.N.', 'cohort_creator_pid': '0000-0003-1864-2151'}], 'cohort_funding': [{'cohort_funder': 'All funders are listed via the Generation R website', 'cohort_funder_identifier': 'https://generationr.nl/algemeen/donateurs/', 'cohort_funder_identifier_type': 'url'}], 'cohort_publisher': [{'cohort_publisher_identifier': 'https://ror.org/018906e22', 'cohort_publisher_identifier_type': 'ROR', 'cohort_publisher_name': 'Erasmus MC'}], 'cohort_references': [{'cohort_reference_citation': 'Growth, development and health from early fetal life until young adulthood: the Generation R Study', 'cohort_reference_identifier': 'https://doi.org/10.1111/j.1365-3016.2003.00521.x', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': '\xa0The Generation R Study: Design and cohort profile', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-006-9022-0', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'The Generation R Study Biobank: a resource for epidemiological studies in children and their parents', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-007-9209-z', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'The Generation R Study: design and cohort update until the age of 4 years', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-008-9309-4', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'The Generation R Study: design and cohort update 2010', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-010-9516-7', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': '\xa0The Generation R Study: design and cohort update 2012', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-012-9735-1', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'Pediatric population-based neuroimaging and the Generation R Study: the intersection of developmental neuroscience and epidemiology', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-013-9768-0', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'The Generation R Study: Biobank update 2015', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-014-9980-6', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'The Generation R Study: design and cohort update 2017', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-016-0224-9', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}]}]
dc_DOI	[{'dc_identifier_type': 'DOI', 'dc_pid': '10.60641/2sxb-6517'}]
dc_constructs	[{'dc_construct': 'physiology'}]
dc_labels	[{'dc_label': 'brain structure'}, {'dc_label': 'neural structure'}, {'dc_label': 'brain volume'}, {'dc_label': 'ventricles'}, {'dc_label': 'basal ganglia'}, {'dc_label': 'neural white matter'}]
dc_modes_of_collection	[{'dc_mode_of_collection': 'MeasurementsAndTests'}]
dc_modes_of_collection_sub	[{'dc_mode_of_collection_sub': 'Echo'}]
measure_age_range	[{'measure_age_month': 0}, {'measure_age_month': 1}, {'measure_age_month': 2}, {'measure_age_month': 3}, {'measure_age_month': 4}, {'measure_age_month': 5}]
study	[{'study_alternate_title': ['Generation R', 'Gen-R'], 'study_language': 'NL', 'study_purpose': 'The purposes of the Generation R study are to (1) describe normal and abnormal growth, development and health from early fetal life to adulthood in a multi-ethnic population; (2) identify (epi-)genetic, biological, social and environmental determinants of this normal and abnormal growth, development and health; and (3) contribute to the development of strategies for optimizing health and healthcare for pregnant women and children.', 'study_time_method': 'Longitudinal', 'study_universe': 'Youth, and their parents, from the general population followed since prenatal life until young adulthood, all born in Rotterdam, the Netherlands.', 'title': 'The Generation R Study', 'study_contact': [{'study_contact_affiliation': 'Erasmus MC', 'study_contact_mail': 'generationr@erasmusmc.nl', 'study_contact_name': 'Generation R Data Management'}], 'study_contributor': [{'study_contributor_affiliation': 'Erasmus MC', 'study_contributor_affiliation_identifier': 'https://ror.org/018906e22', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_identifier_type': 'url', 'study_contributor_name': 'The Generation R Study Group', 'study_contributor_pid': 'https://generationr.nl/algemeen/organisatie/'}], 'study_data_access': [{'study_data_access_URL': 'https://generationr.nl/', 'study_data_access_description': 'Data access requests can be directed to the data management team of the Generation R Study (generationr@erasmusmc.nl), which has a protocol for approving data requests. Because of restrictions based on privacy regulations and informed consent of participants, data cannot be made freely available in a public repository.'}], 'study_funding': [{'study_funder': 'All funders are listed via the Generation R website', 'study_funder_identifier': 'https://generationr.nl/algemeen/donateurs/', 'study_funder_identifier_type': 'url'}], 'study_principal_investigators': [{'study_pi_affiliation': 'Erasmus MC', 'study_pi_affiliation_identifier': 'https://ror.org/018906e22', 'study_pi_affiliation_identifier_scheme': 'ROR', 'study_pi_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_pi_identifier_schemeuri': 'https://orcid.org/', 'study_pi_identifier_type': 'ORCID', 'study_pi_name': 'Bierma - Zeinstra, S.M.A.', 'study_pi_pid': '0000-0003-1280-5896'}, {'study_pi_affiliation': 'Erasmus MC', 'study_pi_affiliation_identifier': 'https://ror.org/018906e22', 'study_pi_affiliation_identifier_scheme': 'ROR', 'study_pi_affiliation_identifier_schemeuri': 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resources	[]
tags	[]
groups	[]
relationships_as_subject	[]
relationships_as_object	[]
tracking_summary	{'total': 0, 'recent': 0}

Gangliothalamic ovoid diameter and ventricular volume

The Generation R Study Cohort study

Generation R: Generation R Cohort

6 weeks Wave