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measure Lung function - Spirometry
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 years 13-14 yearsLung function was measured by spirometry. Measures included FEV1, forced vital capacity (FVC), FEV1/FVC ratio, and forced expiratory flow at 75% of FVC (FEF75).Created June 5, 2024 • Updated September 19, 2024 -
measure LC-MS lipids
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Birth 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.Created June 5, 2024 • Updated September 19, 2024 -
measure Body composition and bone mineral density (Dual X energy absorptiometry)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 years 17-18 yearsDual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).Created June 5, 2024 • Updated September 19, 2024 -
measure Lungs - Allergy test
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 yearsSensitization for birch, cat or dog, or five grass mixture was measured with skin prick tests. Allergy outcomes were categorized into the groups “no inhalant allergic sensitization, no physician-diagnosed inhalant allergy,” “inhalant allergic sensitization but no physician-diagnosed inhalant allergy,” “no inhalant allergic sensitization but...Created June 5, 2024 • Updated September 19, 2024 -
measure Urine sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 yearsFirst-morning, spot, or 24 hour urine sample.Created June 5, 2024 • Updated September 19, 2024 -
measure Actigraphy
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 12 yearsActigraphy estimates children's sleep on both week and weekend days by wearing a tri-axial wrist accelerometer (GENEActiv, Activinsights, UK) for 9 subsequent days on their non-dominant wrist. From the actigraph, sleep duration, sleep efficiency, and sleep arousal can be assessed.Created June 5, 2024 • Updated September 19, 2024 -
measure Cardiac measurements - Magnetic Resonance Imaging
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 9-10 yearsMagnetic Resonance Imaging (MRI) scans were made to assess cardiac structure, diastolic volume, systolic volume, functional cardiac measurements, ejection fraction, stroke volume and aortic diameter.Created June 5, 2024 • Updated September 19, 2024 -
measure Dental development
Study: Generation R Mode of collection: MeasurementsAndTests X-ray Available measurements: Generation R 9-10 years 13-14 yearsPanoramic radiographs were used to ascertain dental development.Created June 5, 2024 • Updated September 19, 2024 -
measure Cardiac and renal structure
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 6 weeks 6 months 2 years 9-10 yearsUltrasound measurements were performed to obtain measures of cardiac and renal structure.Created June 5, 2024 • Updated September 19, 2024 -
measure Blood sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 yearsA blood sample consists of taking an amount of a person's blood from their body.Created June 5, 2024 • Updated September 19, 2024 -
measure Height and weight
Study: Generation R Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 yearsHeight and weight were measured without shoes and heavy clothing.Created June 5, 2024 • Updated September 19, 2024 -
measure Blood pressure
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 yearsBlood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...Created June 5, 2024 • Updated September 19, 2024 -
measure Nasal and nasalpharyngeal swab
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 yearsNasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.Created June 5, 2024 • Updated September 19, 2024 -
measure LC-MS amino acids and carnitines
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Birth 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting amines.Created June 5, 2024 • Updated September 19, 2024 -
measure Hair sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 yearsA hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.Created June 5, 2024 • Updated September 19, 2024 -
measure Diffusion Tensor Imaging (DTI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 7 years 9-10 years 13-14 years 17-18 yearsDiffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.Created June 5, 2024 • Updated September 19, 2024 -
measure Inflammation and immunology markers
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy 5-6 years 9-10 yearsInflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated September 19, 2024 -
measure Eye examination
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 years 17-18 yearsThe eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.Created June 5, 2024 • Updated September 19, 2024 -
measure Metabolic biomarkers
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy 5-6 years 9-10 yearsLipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated September 19, 2024 -
measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 7 years 9-10 years 13-14 years 17-18 yearsFunctional magnetic resonance imaging (MRI) is a non-invasive technique for examining brain activity. Resting state fMRI aims to assess spontaneous brain activity using MRI while the participant is at rest, not performing any specific task. It captures ongoing functional connectivity patterns within the brain.Created June 5, 2024 • Updated September 19, 2024