• measure Urinary osmolality

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Urinary osmolality was measured with a density test (specific gravity) using the Atago refractometer PAL-10S BLT/A+W (Atago, Tokyo, Japan). The refractive index is a ratio of the velocity of light in air to the velocity of light in solution, which is directly proportional to the number of dissolved solids in urine.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Buccal swab

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF1 YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18
     
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    Buccal swabs are collections of buccal cell scrapings obtained by rubbing buds along the inside of the mouth.
    Created October 17, 2024 • Updated October 20, 2024

  • measure LC-MS amines

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Neuropeptides

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Neuropeptides, including Substance P, Beta-endorphin, Dynorphin A, neurotensin, and Leu-enkaphalin, were measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Genotyping (array)

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YC_ADHMRI YE_COG18
     
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    years
    Assessment of single nucleotide polymorphisms (SNPs) as obtained through genotyping arrays.
    Created October 17, 2024 • Updated October 20, 2024

  • measure LC-MS steroid hormones

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB2 YC_ACTION - BB3 YC_BS1
     
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    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting steroid hormones.
    Created October 17, 2024 • Updated October 20, 2024

  • measure GC-MS organic acids

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    years
    Gas chromatography mass spectrometry (GC-MS) platform targeting organic acids.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Liver enzymes

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3
     
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    Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure One Minute Reading Task

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Young Netherlands Twin Register  YS_7 YC_BS1 YC_BS2 YC_BS3
     
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    One subtest of the ‘one minute reading test’ was administered as a measure of technical reading performance, or oral reading fluency. It measures the accuracy and speed of decoding. Children were instructed to read out loud as many words as possible in 1 minute without making errors from a card containing 120 unrelated words.
    Created October 17, 2024 • Updated October 20, 2024

  • measure DNA methylation (array)

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION - BB3
     
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    Assessment of DNA methylation as obtained through DNA methylation arrays.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Zygosity (DNA)

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YS_3 YS_5 YS_7 YS_10 YS_12 YS_DHBQ14 YS_DHBQ16 YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF1 YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18 YS_TRIP age 1-2 YS_TRIP age 3 YS_TRIP age 4 YS_TRIP age 5 YS_TRIP age 7 YS_TRIP age 10 YS_TRIP age 12
     
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    Zygosity typing based on micro-satellite markers, single nucleotide polymorphisms (SNP), or variable number (short) tandem repeats (VNTRs).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Blood sugar markers

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Dipstick

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Urinary dipstick (Siemens, Marburg, Germany) was applied to the first thaw of the urine samples either by dipping in the residual urine volume after aliquoting or by dropping urine on the dipstick to screen for signs of infections in the urine and to measure leukocytes, nitrite, proteins, glucose, and blood presence in the urine.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Inflammation markers

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Oxidative stress markers

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    years
    Oxidative stress markers, including Oxidized DNA/RNA, Total Antioxidant Capacity, and Thiobarbituric acid reactive substances (malondialdehyde), were measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Viral infections

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    years
    Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Urine sample

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YE_COG18
     
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    years
    First-morning, spot, or 24 hour urine sample.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Body composition and bone mineral density (Dual X energy absorptiometry)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
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    Dual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Donating task

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Generation R  7 years
     
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    The Donating Task aims to measure costly prosocial behavior by giving a child the option to donate money to charities or to keep it for themselves. Children are shown a short video from a charity organization on a computer, such as Unicef, SOS Kinderdorpen, or Liliane Fonds. The video features the life of a poor, malnourished child in a developing...
    Created October 17, 2024 • Updated October 20, 2024

  • measure Urine sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 years
     
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    years
    First-morning, spot, or 24 hour urine sample.
    Created October 17, 2024 • Updated October 20, 2024
You can also access this registry using the API (see API Docs).