• measure Anthropometry

    Study:Netherlands Twin Register
    Mode of collection: SelfAdministeredQuestionnaire
    Available measurements:
    Young Netherlands Twin Register  YS_1 YS_2 YS_3 YS_5 YS_7 YS_10 YS_12 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18 YS_TRIP age 1 YS_TRIP age 2 YS_TRIP age 1-2 YS_TRIP age 3 YS_TRIP age 4 YS_TRIP age 5 YS_TRIP age 7 YS_TRIP age 10 YS_TRIP age 12
     
    0
    5
    10
    15
    20
    25
    30
    years
    Anthropometric measurements include height, weight, body mass index (BMI), and body circumferences.
    Created October 17, 2024 Updated October 20, 2024
  • measure Pubertal Development

    Study:Netherlands Twin Register
    Mode of collection: SelfAdministeredQuestionnaire
    Available measurements:
    Young Netherlands Twin Register  YS_1 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YC_ADHMRI YE_COG18 YS_TRIP age 1-2
     
    0
    5
    10
    15
    20
    25
    30
    years
    Pubertal Development was assessed through questions about breast growth, menstruation, shaving, deepening of the voice, and growth spurts.
    Created October 17, 2024 Updated October 20, 2024
  • measure Genotyping array and DNA exome array

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    Assessment of single nucleotide polymorphisms (SNPs) as obtained through genotyping arrays.
    Created October 17, 2024 Updated October 20, 2024
  • measure Skinfold thickness, waist and hip circumference

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  6 weeks 6 months 1 year 2 years 3 years 4 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Skinfold thickness, waist and hip circumference were assessed as an indication of body fat. Skinfold thickness can noninvasively and reliably be measured at various sites of the body using a skinfold caliper. Based on measurements at multiple sites of the body, the total body fat and contribution of fat to the body mass can be estimated.
    Created October 17, 2024 Updated October 20, 2024
  • measure LC-MS lipids

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.
    Created October 17, 2024 Updated October 20, 2024
  • measure Genotyping (array)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    Assessment of micro-satellite markers, single nucleotide polymorphisms (SNP), and variable number (short) tandem repeats (VNTRs) as obtained through genotyping arrays.
    Created October 17, 2024 Updated October 20, 2024
  • measure Urine sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    First-morning, spot, or 24 hour urine sample.
    Created October 17, 2024 Updated October 20, 2024
  • measure Cordblood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    A cordblood sample consists of taking an amount of a person's blood from their umbilical cord. The umbilical cord is the rope-like structure that connects a mother to her unborn baby. After the cord is cut, a health care provider will use a tool called a clamp to stop the cord from bleeding. The provider will then use a needle to withdraw blood from the...
    Created October 17, 2024 Updated October 20, 2024
  • measure Gangliothalamic ovoid diameter and ventricular volume

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  6 weeks
     
    0
    5
    10
    15
    20
    25
    30
    years
    Cranial ultrasound measurements were performed to obtain gangliothalamic ovoid diameter and ventricular volume.
    Created October 17, 2024 Updated October 20, 2024
  • measure Cardiac and renal structure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  6 weeks 6 months 2 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Ultrasound measurements were performed to obtain measures of cardiac and renal structure.
    Created October 17, 2024 Updated October 20, 2024
  • measure Blood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    A blood sample consists of taking an amount of a person's blood from their body.
    Created October 17, 2024 Updated October 20, 2024
  • measure Glucose metabolism

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 5-6 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 Updated October 20, 2024
  • measure Height and weight

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Height and weight were measured without shoes and heavy clothing.
    Created October 17, 2024 Updated October 20, 2024
  • measure Blood pressure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Blood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...
    Created October 17, 2024 Updated October 20, 2024
  • measure Nasal and nasalpharyngeal swab

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Nasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.
    Created October 17, 2024 Updated October 20, 2024
  • measure LC-MS amino acids and carnitines

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created October 17, 2024 Updated October 20, 2024
  • measure DNA methylation (candidate genes)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    DNA methylation of selected candidate genes, such as Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT).
    Created October 17, 2024 Updated October 20, 2024
  • measure DNA methylation (array)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    Assessment of DNA methylation as obtained through DNA methylation arrays.
    Created October 17, 2024 Updated October 20, 2024
  • measure Fetal growth parameters

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy
     
    0
    5
    10
    15
    20
    25
    30
    years
    Fetal growth was assesses via fetal ultrasounds carried out by sonographics during visits to the research center using standardized ultrasound procedures. Fetal growth measures included crown-rump length, head circumference, abdominal circumference, and femur length. Femur length was used as a proxy for fetal length. Estimated fetal weight was calculated...
    Created October 17, 2024 Updated October 20, 2024
  • measure Placental haeomynamics

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  Mid pregnancy Late pregnancy
     
    0
    5
    10
    15
    20
    25
    30
    years
    Placental haeomynamics assesses resistance indices of the uterine and umbilical arteries.
    Created October 17, 2024 Updated October 20, 2024
You can also access this registry using the API (see API Docs).