• measure Zygosity (DNA)

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YS_3 YS_5 YS_7 YS_10 YS_12 YS_DHBQ14 YS_DHBQ16 YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF1 YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18 YS_TRIP age 1-2 YS_TRIP age 3 YS_TRIP age 4 YS_TRIP age 5 YS_TRIP age 7 YS_TRIP age 10 YS_TRIP age 12
     
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    Zygosity typing based on micro-satellite markers, single nucleotide polymorphisms (SNP), or variable number (short) tandem repeats (VNTRs).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Skinfold thickness, waist and hip circumference

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  6 weeks 6 months 1 year 2 years 3 years 4 years
     
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    Skinfold thickness, waist and hip circumference were assessed as an indication of body fat. Skinfold thickness can noninvasively and reliably be measured at various sites of the body using a skinfold caliper. Based on measurements at multiple sites of the body, the total body fat and contribution of fat to the body mass can be estimated.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Body composition and bone mineral density (Dual X energy absorptiometry)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
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    Dual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Urine sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 years
     
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    First-morning, spot, or 24 hour urine sample.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Airway inflammation and airway resistance

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years
     
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    Airway interrupter resistance (Rint) was measured in kilo-pascals per liter during tidal expiration, with occlusion of the airway at peak expiratory flow. Fractional exhaled nitric oxide (FeNO) in parts per billion (ppb) was measured using the NIOX chemiluminescence analyzer.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Heart ultrasound

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  5-6 years
     
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    Heart ultrasound, also known as echocardiography, is a non-invasive medical imaging technique that uses sound waves to create real-time images of the heart's structures, chambers, valves, and blood flow, providing information about its functioning and potential abnormalities.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Forward Color Recall Task

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Generation R  4 years
     
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    The Forward Color Recall task assesses short-term memory in 8 test trials, of which 4 sections are repeated twice. In the task, the child is presented with two circles of colors, and then has to identify the color from a five-color wheel. The test stops if the child fails a trial twice. The total error score can vary between 0 and 8.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Blood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 years
     
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    A blood sample consists of taking an amount of a person's blood from their body.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Glucose metabolism

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 5-6 years
     
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    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Raven's Progressive Matrices Test (RPM) - set I

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Generation R  5-6 years
     
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    Raven's Progressive Matrices (often referred to simply as Raven's Matrices or RPM) is a non-verbal test used to measure general intelligence and abstract reasoning. It is one of the most common tests administered to both groups and individuals ranging from 5-years-olds to the elderly. It consists of 60 multiple choice questions, listed in order of...
    Created October 17, 2024 • Updated October 20, 2024

  • measure PROP taster status

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Generation R  5-6 years
     
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    PROP taster status was determined by using a method developed by Keller et al. (2002). Children were classified as "tasters" or "non-tasters" by giving them 5 ml of 0.56 mmol l-1 solution of PROP (6-n-propylthiouracil; pharmacy of Erasmus MC, Rotterdam, The Netherlands) after which they were asked the question: "Do you taste anything?"
    Created October 17, 2024 • Updated October 20, 2024

  • measure Height and weight

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    Height and weight were measured without shoes and heavy clothing.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Blood pressure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    Blood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...
    Created October 17, 2024 • Updated October 20, 2024

  • measure Nasal and nasalpharyngeal swab

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 years
     
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    Nasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Abdominal fat mass

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  2 years 5-6 years 13-14 years
     
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    Measures of abdominal fat mass were estimated by ultrasound.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Hair sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years
     
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    A hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Snijders-Oomen Niet-verbale Intelligentie Test 2.5-7 jaar revisie (SON-R 2.5-7)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Generation R  5-6 years
     
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    The Snijders-Oomen Niet-verbale Intelligentie Test 2.5-7 jaar revisie (SON-R 2.5-7) is a test battery that assesses intelligence in young children without the need to use language. It consists of the subtest puzzles, categories, patterns, situations, mosaics and analogies, which together assess abstract reasoning and spatial insight abilities.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Arterial stiffness

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years
     
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    Arterial stiffness was measured directly via carotid–femoral pulse‐wave velocity (PWV) and indirectly using pulse pressure (PP).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Inflammation and immunology markers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy 5-6 years 9-10 years
     
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    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Eye examination

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
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    The eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.
    Created October 17, 2024 • Updated October 20, 2024
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