• measure Cardiac and renal structure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  6 weeks 6 months 2 years 9-10 years
     
    0
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    30
    years
    Ultrasound measurements were performed to obtain measures of cardiac and renal structure.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    A blood sample consists of taking an amount of a person's blood from their body.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Glucose metabolism

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 5-6 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Height and weight

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Height and weight were measured without shoes and heavy clothing.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood pressure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
    0
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    25
    30
    years
    Blood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Nasal and nasalpharyngeal swab

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 years
     
    0
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    30
    years
    Nasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Abdominal fat mass

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  2 years 5-6 years 13-14 years
     
    0
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    30
    years
    Measures of abdominal fat mass were estimated by ultrasound.
    Created June 5, 2024 • Updated September 19, 2024

  • measure LC-MS amino acids and carnitines

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 9-10 years
     
    0
    5
    10
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    25
    30
    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created June 5, 2024 • Updated September 19, 2024

  • measure DNA methylation (candidate genes)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    DNA methylation of selected candidate genes, such as Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Electroencephalography (EEG) - Visuomotor adjustment paradigm

    Study:Generation R
    Mode of collection: MeasurementsAndTests    EEG Behavioral/cognitive task
    Available measurements:
    Generation R  17-18 years
     
    0
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    30
    years
    Electrocardiography (EEG) was measured while participants performed a visuomotor adjustment paradigm to measure motor control.
    Created June 5, 2024 • Updated September 19, 2024

  • measure DNA methylation (array)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    Assessment of DNA methylation as obtained through DNA methylation arrays.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Hair sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    A hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Fetal growth parameters

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy
     
    0
    5
    10
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    20
    25
    30
    years
    Fetal growth was assesses via fetal ultrasounds carried out by sonographics during visits to the research center using standardized ultrasound procedures. Fetal growth measures included crown-rump length, head circumference, abdominal circumference, and femur length. Femur length was used as a proxy for fetal length. Estimated fetal weight was calculated...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Placental haeomynamics

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  Mid pregnancy Late pregnancy
     
    0
    5
    10
    15
    20
    25
    30
    years
    Placental haeomynamics assesses resistance indices of the uterine and umbilical arteries.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Arterial stiffness

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years
     
    0
    5
    10
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    25
    30
    years
    Arterial stiffness was measured directly via carotid–femoral pulse‐wave velocity (PWV) and indirectly using pulse pressure (PP).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Diffusion Tensor Imaging (DTI)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Generation R  7 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Diffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Fetal brain development

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy
     
    0
    5
    10
    15
    20
    25
    30
    years
    Fetal brain development was assessed via fetal ultrasounds carried out by sonographers during visits to the research center using standardized techniques. Brain measures included transcerebellar diameter and atrial width of lateral ventricles and were done. The atrial width of the lateral ventricle is the widest diameter of the atrium of one of the...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Inflammation and immunology markers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy 5-6 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Eye examination

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    The eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Infant vagal modulation (electrocardiography)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    ECG
    Available measurements:
    Generation R  1 year
     
    0
    5
    10
    15
    20
    25
    30
    years
    Variations in heart rate influenced by the vagus nerve were assessed via electrocardiography (ECG).
    Created June 5, 2024 • Updated September 19, 2024
You can also access this registry using the API (see API Docs).