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measure Heart ultrasound
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 5-6 yearsHeart ultrasound, also known as echocardiography, is a non-invasive medical imaging technique that uses sound waves to create real-time images of the heart's structures, chambers, valves, and blood flow, providing information about its functioning and potential abnormalities.Created October 17, 2024 • Updated October 20, 2024 -
measure Muscle function and bone strength (Mechanography)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 17-18 yearsMuscle function and bone strength were assessed using mechanography. This includes a mechanographic record of jumping movements on a specially designed springboard. Relevant functional parameters such as strength and spot force are measured to determine coordination, muscle function and muscle-bone relationship.Created October 17, 2024 • Updated October 20, 2024 -
measure Actigraphy
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 12 yearsActigraphy estimates children's sleep on both week and weekend days by wearing a tri-axial wrist accelerometer (GENEActiv, Activinsights, UK) for 9 subsequent days on their non-dominant wrist. From the actigraph, sleep duration, sleep efficiency, and sleep arousal can be assessed.Created October 17, 2024 • Updated October 20, 2024 -
measure Cordblood sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R BirthA cordblood sample consists of taking an amount of a person's blood from their umbilical cord. The umbilical cord is the rope-like structure that connects a mother to her unborn baby. After the cord is cut, a health care provider will use a tool called a clamp to stop the cord from bleeding. The provider will then use a needle to withdraw blood from the...Created October 17, 2024 • Updated October 20, 2024 -
measure Exercise test - Steep Ramp Test
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 13-14 yearsThe Steep Ramp Test is a short maximal exercise test that measures the peak work rate (WRpeak), which is a valid and reliable estimation of the maximal aerobic exercise capacity and thus cardiorespiratory fitness.Created October 17, 2024 • Updated October 20, 2024 -
measure Cardiac measurements - Magnetic Resonance Imaging
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 9-10 yearsMagnetic Resonance Imaging (MRI) scans were made to assess cardiac structure, diastolic volume, systolic volume, functional cardiac measurements, ejection fraction, stroke volume and aortic diameter.Created October 17, 2024 • Updated October 20, 2024 -
measure Dental development
Study: Generation R Mode of collection: MeasurementsAndTests X-ray Available measurements: Generation R 9-10 years 13-14 yearsPanoramic radiographs were used to ascertain dental development.Created October 17, 2024 • Updated October 20, 2024 -
measure Gangliothalamic ovoid diameter and ventricular volume
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 6 weeksCranial ultrasound measurements were performed to obtain gangliothalamic ovoid diameter and ventricular volume.Created October 17, 2024 • Updated October 20, 2024 -
measure Cardiac and renal structure
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 6 weeks 6 months 2 years 9-10 yearsUltrasound measurements were performed to obtain measures of cardiac and renal structure.Created October 17, 2024 • Updated October 20, 2024 -
measure Blood sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 yearsA blood sample consists of taking an amount of a person's blood from their body.Created October 17, 2024 • Updated October 20, 2024 -
measure Glucose metabolism
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Birth 5-6 yearsBlood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Height and weight
Study: Generation R Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 yearsHeight and weight were measured without shoes and heavy clothing.Created October 17, 2024 • Updated October 20, 2024 -
measure Blood pressure
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 yearsBlood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...Created October 17, 2024 • Updated October 20, 2024 -
measure Nasal and nasalpharyngeal swab
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 yearsNasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.Created October 17, 2024 • Updated October 20, 2024 -
measure Abdominal fat mass
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 2 years 5-6 years 13-14 yearsMeasures of abdominal fat mass were estimated by ultrasound.Created October 17, 2024 • Updated October 20, 2024 -
measure Pubertal Development Scale (PDS)
Study: Generation R Mode of collection: SelfAdministeredQuestionnaire Available measurements: Generation R 13-14 yearsThe Pubertal Development Scale (PDS) assesses the development of secondary sexual characteristics, such as growth spurts, body hair growth, skin changes, breast development and menarche in girls, and voice changes and growth of testes in boys.Created October 17, 2024 • Updated October 20, 2024 -
measure LC-MS amino acids and carnitines
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Birth 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting amines.Created October 17, 2024 • Updated October 20, 2024 -
measure DNA methylation (candidate genes)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R BirthDNA methylation of selected candidate genes, such as Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT).Created October 17, 2024 • Updated October 20, 2024 -
measure Electroencephalography (EEG) - Visuomotor adjustment paradigm
Study: Generation R Mode of collection: MeasurementsAndTests EEG Behavioral/cognitive task Available measurements: Generation R 17-18 yearsElectrocardiography (EEG) was measured while participants performed a visuomotor adjustment paradigm to measure motor control.Created October 17, 2024 • Updated October 20, 2024 -
measure DNA methylation (array)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R BirthAssessment of DNA methylation as obtained through DNA methylation arrays.Created October 17, 2024 • Updated October 20, 2024