• measure Diffusion Tensor Imaging (DTI)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Generation R  7 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Diffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Finger tapping task

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Generation R  9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    The Finger Tapping Task is a computerized task that assesses motor control, speed and lateralized coordination. During the task, children have to tap switching between their right, left, or both index fingers as quickly as possible for 10 seconds. A total of five trials are measured, starting with a visual and an auditory queue. The total number of finger...
    Created October 17, 2024 • Updated October 20, 2024

  • measure Inflammation and immunology markers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy 5-6 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Eye examination

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    The eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Metabolic biomarkers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy 5-6 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Generation R  7 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Functional magnetic resonance imaging (MRI) is a non-invasive technique for examining brain activity. Resting state fMRI aims to assess spontaneous brain activity using MRI while the participant is at rest, not performing any specific task. It captures ongoing functional connectivity patterns within the brain.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Reading the Mind in the Eyes Test (RMET)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Generation R  9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    The Reading the Mind in the Eyes Test (RMET) assesses the ability to recognize complex mental states as expressed by human eyes. Participants pick one of four options (e.g. puzzled, nervous, insisting or contemplative) which they think best describes what the person in each photograph is thinking or feeling.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Stool microbiota

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Stool microbiota encompasses the diverse community of microorganisms residing in the gastrointestinal tract that play crucial roles in digestion, immunity, and overall health.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Intima-media thickness

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  9-10 years 13-14 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Thickness of the carotid intima media was assessed through ultrasonographic recordings.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Biomarkers in endocrinology/nephrology

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy 5-6 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Structural Magnetic Resonance Imaging (MRI)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Generation R  7 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Structural magnetic resonance imaging (MRI) is a non-invasive technique for examining the anatomy and pathology of the brain (as opposed to using functional magnetic resonance imaging [fMRI] to examine brain activity).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Walking Backwards task

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Generation R  9-10 years
     
    0
    5
    10
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    20
    25
    30
    years
    The Walking Backwards task (Rückwärts Balancieren) from the Body Coordination Test for Children (Korperkoordinationstest für Kinder) assesses balancing ability. Children are asked to walk backwards on three different balance beams. They start with a forwards practice, after which they have to walk backwards twice.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Respiratory Sinus Arrhythmia (RSA)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    ECG
    Available measurements:
    Population cohort  POP - T1 POP - T3

    Clinical cohort  CC - T1 CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Respiratory sinus arrhythmia is part of the autonomic nervous system and serves to optimize gas exchange between the lungs and the circulatory system. It was measured through an electrocardiogram (ECG) and included respiratory sinus arrhythmia at rest, during orthostatic stress, and during the Spatial Orienting Task and Bangor Gambling Task.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Saliva sample

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T1

    Clinical cohort  CC - T1
     
    0
    5
    10
    15
    20
    25
    30
    years
    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Baroreflex Sensitivity (BRS)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T1 POP - T3

    Clinical cohort  CC - T1 CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Baroreflex Sensitivity (BRS) assessment using an electrocardiogram (ECG). The baroreflex is part of the autonomic nervous system and helps to maintain the blood pressure at a constant level. Measurements include baroreflex sensitivity at rest, during orthostatic stress, and during the Spatial Orienting Task and Bangor Gambling Task.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Steroid hormones - Cortisol

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T1 POP - T3

    Clinical cohort  CC - T1 CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Steroid hormones, for instance Testosterone, Estrogen, Dehydroepiandrosterone (DHEA), and Cortisol, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Blood pressure

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T1 POP - T3

    Clinical cohort  CC - T1 CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Blood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...
    Created October 17, 2024 • Updated October 20, 2024

  • measure Heart rate

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T1 POP - T3

    Clinical cohort  CC - T1 CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Heart rate is the number of times a heart beats per minute and normally ranges between 60 and 100 times for adults. Heart rate variability is the time fluctuation between heart beats.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Skinfold thickness

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T1 POP - T3 POP - T4

    Clinical cohort  CC - T1 CC - T3 CC - T4
     
    0
    5
    10
    15
    20
    25
    30
    years
    Skinfold thickness is an assessment of body fat which can noninvasively and reliably be measured at various sites of the body using a skinfold caliper. Based on measurements at multiple sites of the body, the total body fat and contribution of fat to the body mass can be estimated.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Wechsler Intelligence Scale for Children (WISC-R)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task
    Available measurements:
    Population cohort  POP - T1

    Clinical cohort  CC - T1
     
    0
    5
    10
    15
    20
    25
    30
    years
    The Wechsler Intelligence Scale for Children (WISC) is an IQ test for children 6-17 years of age to determine general intelligence. It generates a full scale IQ (formerly known as an intelligence quotient or IQ score) that represents a child's general intellectual ability. The most common primary index scores are the Verbal Comprehension Index, the Visual...
    Created October 17, 2024 • Updated October 20, 2024
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