• measure Urine sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 years
     
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    First-morning, spot, or 24 hour urine sample.
    Created June 5, 2024 Updated September 19, 2024
  • measure Glucose metabolism

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 5-6 years
     
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    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 Updated September 19, 2024
  • measure Inflammation and immunology markers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy 5-6 years 9-10 years
     
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    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 Updated September 19, 2024
  • measure Biomarkers in endocrinology/nephrology

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy 5-6 years 9-10 years
     
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    Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 Updated September 19, 2024
  • measure Urinary osmolality

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Urinary osmolality was measured with a density test (specific gravity) using the Atago refractometer PAL-10S BLT/A+W (Atago, Tokyo, Japan). The refractive index is a ratio of the velocity of light in air to the velocity of light in solution, which is directly proportional to the number of dissolved solids in urine.
    Created June 5, 2024 Updated June 20, 2024
  • measure LC-MS amines

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created June 5, 2024 Updated June 20, 2024
  • measure Neuropeptides

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Neuropeptides, including Substance P, Beta-endorphin, Dynorphin A, neurotensin, and Leu-enkaphalin, were measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 Updated June 20, 2024
  • measure LC-MS steroid hormones

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB2 YC_ACTION - BB3 YC_BS1
     
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    Liquid chromatography mass spectrometry (LC-MS) platform targeting steroid hormones.
    Created June 5, 2024 Updated June 20, 2024
  • measure GC-MS organic acids

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    years
    Gas chromatography mass spectrometry (GC-MS) platform targeting organic acids.
    Created June 5, 2024 Updated June 20, 2024
  • measure Liver enzymes

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3
     
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    years
    Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 Updated June 20, 2024
  • measure Blood sugar markers

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 Updated June 20, 2024
  • measure Dipstick

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Urinary dipstick (Siemens, Marburg, Germany) was applied to the first thaw of the urine samples either by dipping in the residual urine volume after aliquoting or by dropping urine on the dipstick to screen for signs of infections in the urine and to measure leukocytes, nitrite, proteins, glucose, and blood presence in the urine.
    Created June 5, 2024 Updated June 20, 2024
  • measure Inflammation markers

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
    0
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    30
    years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 Updated June 20, 2024
  • measure Oxidative stress markers

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Oxidative stress markers, including Oxidized DNA/RNA, Total Antioxidant Capacity, and Thiobarbituric acid reactive substances (malondialdehyde), were measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 Updated June 20, 2024
  • measure Viral infections

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 Updated June 20, 2024
  • measure Urine sample

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YE_COG18
     
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    25
    30
    years
    First-morning, spot, or 24 hour urine sample.
    Created June 5, 2024 Updated June 20, 2024
You can also access this registry using the API (see API Docs).