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measure Anthropometry
Study: Netherlands Twin Register Mode of collection: SelfAdministeredQuestionnaire Available measurements: Young Netherlands Twin Register YS_1 YS_2 YS_3 YS_5 YS_7 YS_10 YS_12 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18 YS_TRIP age 1 YS_TRIP age 2 YS_TRIP age 1-2 YS_TRIP age 3 YS_TRIP age 4 YS_TRIP age 5 YS_TRIP age 7 YS_TRIP age 10 YS_TRIP age 12Anthropometric measurements include height, weight, body mass index (BMI), and body circumferences.Created October 17, 2024 • Updated October 20, 2024 -
measure Flexibility
Study: Netherlands Twin Register Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YE_FITNSSPhysical flexibility was measured using a standard sit-and-reach box (Baseline Sit-and-reach Trunk Flexibility Box, Fabrication Enterprises Inc., USA).Created October 17, 2024 • Updated October 20, 2024 -
measure Box marking test
Study: Netherlands Twin Register Mode of collection: MeasurementsAndTests Behavioral/cognitive task Available measurements: Young Netherlands Twin Register YC_BS2 YE_COG18The Box Marking Test assesses the degree of handedness, by measuring hand skill by the number of boxes the participant can tick on a printed sheet in one minute. Each hand was tested separately, the right hand being tested first. A ratio between both hands was determined, by subtracting the right-hand score from the left-hand score, divided by the sum of...Created October 17, 2024 • Updated October 20, 2024 -
measure Diffusion Tensor Imaging (DTI)
Study: Netherlands Twin Register Mode of collection: MeasurementsAndTests MRI Available measurements: Young Netherlands Twin Register YC_BS1 YC_BS2 YC_BS3Diffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.Created October 17, 2024 • Updated October 20, 2024 -
measure Pubertal Development
Study: Netherlands Twin Register Mode of collection: SelfAdministeredQuestionnaire Available measurements: Young Netherlands Twin Register YS_1 YS_DHBQP YS_DHBQ14 YS_DHBQ16 YS_DHBQ18 YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YC_ADHMRI YE_COG18 YS_TRIP age 1-2Pubertal Development was assessed through questions about breast growth, menstruation, shaving, deepening of the voice, and growth spurts.Created October 17, 2024 • Updated October 20, 2024 -
measure Blood sample
Study: Netherlands Twin Register Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YE_COG18A blood sample consists of taking an amount of a person's blood from their body.Created October 17, 2024 • Updated October 20, 2024 -
measure Balance Error Scoring System (BESS)
Study: Netherlands Twin Register Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Netherlands Twin Register YE_FITNSSThe Balance Error Scoring System (BESS) was used to assess balance under 3 testing stances: double leg, single leg (non-dominant leg) and tandem (dominant foot in front of the non-dominant foot in heel-to-toe fashion) on 2 surfaces (ground and foam pad). The total score was the total number of errors across the six 20-second repeated measures.Created October 17, 2024 • Updated October 20, 2024 -
measure Genotyping array and DNA exome array
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy BirthAssessment of single nucleotide polymorphisms (SNPs) as obtained through genotyping arrays.Created October 17, 2024 • Updated October 20, 2024 -
measure Lung function - Spirometry
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 years 13-14 yearsLung function was measured by spirometry. Measures included FEV1, forced vital capacity (FVC), FEV1/FVC ratio, and forced expiratory flow at 75% of FVC (FEF75).Created October 17, 2024 • Updated October 20, 2024 -
measure Skinfold thickness, waist and hip circumference
Study: Generation R Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Generation R 6 weeks 6 months 1 year 2 years 3 years 4 yearsSkinfold thickness, waist and hip circumference were assessed as an indication of body fat. Skinfold thickness can noninvasively and reliably be measured at various sites of the body using a skinfold caliper. Based on measurements at multiple sites of the body, the total body fat and contribution of fat to the body mass can be estimated.Created October 17, 2024 • Updated October 20, 2024 -
measure Electrocardiography (ECG)
Study: Generation R Mode of collection: MeasurementsAndTests ECG Available measurements: Generation R 17-18 yearsElectrocardiography (ECG) is a medical diagnostic technique that records the electrical activity of the heart over time, enabling the assessment of its rhythm, rate, and overall cardiovascular health.Created October 17, 2024 • Updated October 20, 2024 -
measure LC-MS lipids
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Birth 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.Created October 17, 2024 • Updated October 20, 2024 -
measure Body composition and bone mineral density (Dual X energy absorptiometry)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 years 17-18 yearsDual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).Created October 17, 2024 • Updated October 20, 2024 -
measure Dental plaque and oral microbiome
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 13-14 years 17-18 yearsDental plaque samples were collected by rubbing a cotton swab over the buccal sides of the right lower permanent molars. DNA was isolated from the dental plaque swabs.Created October 17, 2024 • Updated October 20, 2024 -
measure Tanner Scale
Study: Generation R Mode of collection: SelfAdministeredQuestionnaire Available measurements: Generation R 13-14 yearsThe Tanner Scale describes, both pictorially and descriptively, the external changes that occur in the time period between the onset of puberty and the achievement of full maturity for both girls and boys. Characterizations of pubertal status are assessed by breast development in girls, genital development in boys and pubic hair growth in both. The Tanner...Created October 17, 2024 • Updated October 20, 2024 -
measure Lungs - Allergy test
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 yearsSensitization for birch, cat or dog, or five grass mixture was measured with skin prick tests. Allergy outcomes were categorized into the groups “no inhalant allergic sensitization, no physician-diagnosed inhalant allergy,” “inhalant allergic sensitization but no physician-diagnosed inhalant allergy,” “no inhalant allergic sensitization but...Created October 17, 2024 • Updated October 20, 2024 -
measure Genotyping (array)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R BirthAssessment of micro-satellite markers, single nucleotide polymorphisms (SNP), and variable number (short) tandem repeats (VNTRs) as obtained through genotyping arrays.Created October 17, 2024 • Updated October 20, 2024 -
measure Bone mineral density and geometry of the tibia (Peripheral Quantitative Compu...
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 13-14 years 17-18 yearsMeasurements of bone mineral density and the Geometry of the tibia by peripheral quantitative computed tomography (CT).Created October 17, 2024 • Updated October 20, 2024 -
measure Urine sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 yearsFirst-morning, spot, or 24 hour urine sample.Created October 17, 2024 • Updated October 20, 2024 -
measure Airway inflammation and airway resistance
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 yearsAirway interrupter resistance (Rint) was measured in kilo-pascals per liter during tidal expiration, with occlusion of the airway at peak expiratory flow. Fractional exhaled nitric oxide (FeNO) in parts per billion (ppb) was measured using the NIOX chemiluminescence analyzer.Created October 17, 2024 • Updated October 20, 2024