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measure Lung function - Spirometry
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 years 13-14 yearsLung function was measured by spirometry. Measures included FEV1, forced vital capacity (FVC), FEV1/FVC ratio, and forced expiratory flow at 75% of FVC (FEF75).Created June 5, 2024 • Updated September 19, 2024 -
measure Body composition and bone mineral density (Dual X energy absorptiometry)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 years 17-18 yearsDual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).Created June 5, 2024 • Updated September 19, 2024 -
measure Dental plaque and oral microbiome
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 13-14 years 17-18 yearsDental plaque samples were collected by rubbing a cotton swab over the buccal sides of the right lower permanent molars. DNA was isolated from the dental plaque swabs.Created June 5, 2024 • Updated September 19, 2024 -
measure Bone mineral density and geometry of the tibia (Peripheral Quantitative Compu...
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 13-14 years 17-18 yearsMeasurements of bone mineral density and the Geometry of the tibia by peripheral quantitative computed tomography (CT).Created June 5, 2024 • Updated September 19, 2024 -
measure Urine sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 yearsFirst-morning, spot, or 24 hour urine sample.Created June 5, 2024 • Updated September 19, 2024 -
measure Exercise test - Steep Ramp Test
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 13-14 yearsThe Steep Ramp Test is a short maximal exercise test that measures the peak work rate (WRpeak), which is a valid and reliable estimation of the maximal aerobic exercise capacity and thus cardiorespiratory fitness.Created June 5, 2024 • Updated September 19, 2024 -
measure Audiometry
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 years 13-14 years 17-18 yearsAudiometry measurements evaluate an individual's hearing abilities, with pure-tone audiometry assessing hearing sensitivity across different frequencies and intensities, and tympanometry measuring the middle ear's response to changes in air pressure.Created June 5, 2024 • Updated September 19, 2024 -
measure Blood sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 yearsA blood sample consists of taking an amount of a person's blood from their body.Created June 5, 2024 • Updated September 19, 2024 -
measure Blood pressure
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 yearsBlood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...Created June 5, 2024 • Updated September 19, 2024 -
measure Hair sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 yearsA hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.Created June 5, 2024 • Updated September 19, 2024 -
measure Eye examination
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 years 17-18 yearsThe eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.Created June 5, 2024 • Updated September 19, 2024 -
measure Intima-media thickness
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 years 13-14 yearsThickness of the carotid intima media was assessed through ultrasonographic recordings.Created June 5, 2024 • Updated September 19, 2024 -
measure Viral infections - Herpes Simplex Virus 1 (HSV-1)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Blood sugar markers - Insulin
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Buccal swab
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3
The Next Generation NEXT - T3Buccal swabs are collections of buccal cell scrapings obtained by rubbing buds along the inside of the mouth.Created June 5, 2024 • Updated June 20, 2024 -
measure Shuttle run test
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3The shuttle run test is a validated assessment of physcial fitness. In the task, participants have to continuously run between two lines that are twenty meters apart and reach the lines before a recorded beep. Measurements include performance, heart rate, heart rate variability, and lung capacity.Created June 5, 2024 • Updated June 20, 2024 -
measure Startle Reflex Task
Study: TRAILS Mode of collection: MeasurementsAndTests Behavioral/cognitive task Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3The Startle Reflex Task is an assessment of physiological and subjective stress reactivity. In the task, participants have to watch nine short videos: 3 videos for habituation, 2 positive, 2 neutral and 2 unpleasant videos. During the videos, participants are startled by a white noise, and they are instructed to ignore them. After the task, participants...Created June 5, 2024 • Updated June 20, 2024 -
measure Peptide hormones - Adrenocorticotropic Hormone (ACTH)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Peptide hormones, for instance Adrenocorticotropic Hormone (ACTH, pituitary hormone), Alpha-Melanocyte-Stimulating Hormone (α-MSH, Melanocortin), Luteinizing Hormone (LH), Cholecytokinin, and Follicle Stimulating Hormone (FSH), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Lipids - Cholesterol
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Baroreflex Sensitivity (BRS)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T1 POP - T3
Clinical cohort CC - T1 CC - T3Baroreflex Sensitivity (BRS) assessment using an electrocardiogram (ECG). The baroreflex is part of the autonomic nervous system and helps to maintain the blood pressure at a constant level. Measurements include baroreflex sensitivity at rest, during orthostatic stress, and during the Spatial Orienting Task and Bangor Gambling Task.Created June 5, 2024 • Updated June 20, 2024