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measure Eye examination
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 years 17-18 yearsThe eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.Created June 5, 2024 • Updated September 19, 2024 -
measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 7 years 9-10 years 13-14 years 17-18 yearsFunctional magnetic resonance imaging (MRI) is a non-invasive technique for examining brain activity. Resting state fMRI aims to assess spontaneous brain activity using MRI while the participant is at rest, not performing any specific task. It captures ongoing functional connectivity patterns within the brain.Created June 5, 2024 • Updated September 19, 2024 -
measure Intima-media thickness
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 years 13-14 yearsThickness of the carotid intima media was assessed through ultrasonographic recordings.Created June 5, 2024 • Updated September 19, 2024 -
measure Dental caries and developmental defect of enamel
Study: Generation R Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Generation R 5-6 years 13-14 years 17-18 yearsIntra-oral photographs were made using an intra-oral camera, and were scored for dental caries and developmental defects of enamel by dentists.Created June 5, 2024 • Updated September 19, 2024 -
measure Structural Magnetic Resonance Imaging (MRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 7 years 9-10 years 13-14 years 17-18 yearsStructural magnetic resonance imaging (MRI) is a non-invasive technique for examining the anatomy and pathology of the brain (as opposed to using functional magnetic resonance imaging [fMRI] to examine brain activity).Created June 5, 2024 • Updated September 19, 2024 -
measure Viral infections - Herpes Simplex Virus 1 (HSV-1)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Blood sugar markers - Insulin
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Buccal swab
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3
The Next Generation NEXT - T3Buccal swabs are collections of buccal cell scrapings obtained by rubbing buds along the inside of the mouth.Created June 5, 2024 • Updated June 20, 2024 -
measure Eyeblink reflex
Study: TRAILS Mode of collection: MeasurementsAndTests EMG Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Eyeblink reflexes were assessed using electromyography (EMG), both at rest and during the Startle Reflex Task.Created June 5, 2024 • Updated June 20, 2024 -
measure Waist and hip circumference
Study: TRAILS Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Population cohort POP - T3 POP - T4 POP - T5
Clinical cohort CC - T3 CC - T4 CC - T5Waist and hip circumference were assessed using a tape measure.Created June 5, 2024 • Updated June 20, 2024 -
measure Shuttle run test
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3The shuttle run test is a validated assessment of physcial fitness. In the task, participants have to continuously run between two lines that are twenty meters apart and reach the lines before a recorded beep. Measurements include performance, heart rate, heart rate variability, and lung capacity.Created June 5, 2024 • Updated June 20, 2024 -
measure Respiratory Sinus Arrhythmia (RSA)
Study: TRAILS Mode of collection: MeasurementsAndTests ECG Available measurements: Population cohort POP - T1 POP - T3
Clinical cohort CC - T1 CC - T3Respiratory sinus arrhythmia is part of the autonomic nervous system and serves to optimize gas exchange between the lungs and the circulatory system. It was measured through an electrocardiogram (ECG) and included respiratory sinus arrhythmia at rest, during orthostatic stress, and during the Spatial Orienting Task and Bangor Gambling Task.Created June 5, 2024 • Updated June 20, 2024 -
measure Startle Reflex Task
Study: TRAILS Mode of collection: MeasurementsAndTests Behavioral/cognitive task Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3The Startle Reflex Task is an assessment of physiological and subjective stress reactivity. In the task, participants have to watch nine short videos: 3 videos for habituation, 2 positive, 2 neutral and 2 unpleasant videos. During the videos, participants are startled by a white noise, and they are instructed to ignore them. After the task, participants...Created June 5, 2024 • Updated June 20, 2024 -
measure Peptide hormones - Adrenocorticotropic Hormone (ACTH)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Peptide hormones, for instance Adrenocorticotropic Hormone (ACTH, pituitary hormone), Alpha-Melanocyte-Stimulating Hormone (α-MSH, Melanocortin), Luteinizing Hormone (LH), Cholecytokinin, and Follicle Stimulating Hormone (FSH), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Lipids - Cholesterol
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Baroreflex Sensitivity (BRS)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T1 POP - T3
Clinical cohort CC - T1 CC - T3Baroreflex Sensitivity (BRS) assessment using an electrocardiogram (ECG). The baroreflex is part of the autonomic nervous system and helps to maintain the blood pressure at a constant level. Measurements include baroreflex sensitivity at rest, during orthostatic stress, and during the Spatial Orienting Task and Bangor Gambling Task.Created June 5, 2024 • Updated June 20, 2024 -
measure Inflammation markers - C-reactive Protein (CRP)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Blood sugar markers - Glucose
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Viral infections - Epstein-Barr Virus (EBV)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024 -
measure Steroid hormones - Cortisol
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T1 POP - T3
Clinical cohort CC - T1 CC - T3Steroid hormones, for instance Testosterone, Estrogen, Dehydroepiandrosterone (DHEA), and Cortisol, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created June 5, 2024 • Updated June 20, 2024