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measure Lung function - Spirometry
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 years 13-14 yearsLung function was measured by spirometry. Measures included FEV1, forced vital capacity (FVC), FEV1/FVC ratio, and forced expiratory flow at 75% of FVC (FEF75).Created October 17, 2024 • Updated October 20, 2024 -
measure LC-MS lipids
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Birth 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.Created October 17, 2024 • Updated October 20, 2024 -
measure Body composition and bone mineral density (Dual X energy absorptiometry)
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 years 17-18 yearsDual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).Created October 17, 2024 • Updated October 20, 2024 -
measure Lungs - Allergy test
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 9-10 yearsSensitization for birch, cat or dog, or five grass mixture was measured with skin prick tests. Allergy outcomes were categorized into the groups “no inhalant allergic sensitization, no physician-diagnosed inhalant allergy,” “inhalant allergic sensitization but no physician-diagnosed inhalant allergy,” “no inhalant allergic sensitization but...Created October 17, 2024 • Updated October 20, 2024 -
measure Urine sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 yearsFirst-morning, spot, or 24 hour urine sample.Created October 17, 2024 • Updated October 20, 2024 -
measure Airway inflammation and airway resistance
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 yearsAirway interrupter resistance (Rint) was measured in kilo-pascals per liter during tidal expiration, with occlusion of the airway at peak expiratory flow. Fractional exhaled nitric oxide (FeNO) in parts per billion (ppb) was measured using the NIOX chemiluminescence analyzer.Created October 17, 2024 • Updated October 20, 2024 -
measure Heart ultrasound
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 5-6 yearsHeart ultrasound, also known as echocardiography, is a non-invasive medical imaging technique that uses sound waves to create real-time images of the heart's structures, chambers, valves, and blood flow, providing information about its functioning and potential abnormalities.Created October 17, 2024 • Updated October 20, 2024 -
measure Cardiac measurements - Magnetic Resonance Imaging
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 9-10 yearsMagnetic Resonance Imaging (MRI) scans were made to assess cardiac structure, diastolic volume, systolic volume, functional cardiac measurements, ejection fraction, stroke volume and aortic diameter.Created October 17, 2024 • Updated October 20, 2024 -
measure Dental development
Study: Generation R Mode of collection: MeasurementsAndTests X-ray Available measurements: Generation R 9-10 years 13-14 yearsPanoramic radiographs were used to ascertain dental development.Created October 17, 2024 • Updated October 20, 2024 -
measure Cardiac and renal structure
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 6 weeks 6 months 2 years 9-10 yearsUltrasound measurements were performed to obtain measures of cardiac and renal structure.Created October 17, 2024 • Updated October 20, 2024 -
measure Blood sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 yearsA blood sample consists of taking an amount of a person's blood from their body.Created October 17, 2024 • Updated October 20, 2024 -
measure Glucose metabolism
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Birth 5-6 yearsBlood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Height and weight
Study: Generation R Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 yearsHeight and weight were measured without shoes and heavy clothing.Created October 17, 2024 • Updated October 20, 2024 -
measure Blood pressure
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 yearsBlood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...Created October 17, 2024 • Updated October 20, 2024 -
measure Nasal and nasalpharyngeal swab
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 yearsNasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.Created October 17, 2024 • Updated October 20, 2024 -
measure Abdominal fat mass
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 2 years 5-6 years 13-14 yearsMeasures of abdominal fat mass were estimated by ultrasound.Created October 17, 2024 • Updated October 20, 2024 -
measure LC-MS amino acids and carnitines
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Birth 9-10 yearsLiquid chromatography mass spectrometry (LC-MS) platform targeting amines.Created October 17, 2024 • Updated October 20, 2024 -
measure Hair sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 yearsA hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.Created October 17, 2024 • Updated October 20, 2024 -
measure Arterial stiffness
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 yearsArterial stiffness was measured directly via carotid–femoral pulse‐wave velocity (PWV) and indirectly using pulse pressure (PP).Created October 17, 2024 • Updated October 20, 2024 -
measure Diffusion Tensor Imaging (DTI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 7 years 9-10 years 13-14 years 17-18 yearsDiffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.Created October 17, 2024 • Updated October 20, 2024