• measure Lung function - Spirometry

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  9-10 years 13-14 years
     
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    Lung function was measured by spirometry. Measures included FEV1, forced vital capacity (FVC), FEV1/FVC ratio, and forced expiratory flow at 75% of FVC (FEF75).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Body composition and bone mineral density (Dual X energy absorptiometry)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
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    Dual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Dental plaque and oral microbiome

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  13-14 years 17-18 years
     
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    Dental plaque samples were collected by rubbing a cotton swab over the buccal sides of the right lower permanent molars. DNA was isolated from the dental plaque swabs.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Bone mineral density and geometry of the tibia (Peripheral Quantitative Compu...

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  13-14 years 17-18 years
     
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    Measurements of bone mineral density and the Geometry of the tibia by peripheral quantitative computed tomography (CT).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Urine sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 years
     
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    First-morning, spot, or 24 hour urine sample.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Actigraphy

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  12 years
     
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    Actigraphy estimates children's sleep on both week and weekend days by wearing a tri-axial wrist accelerometer (GENEActiv, Activinsights, UK) for 9 subsequent days on their non-dominant wrist. From the actigraph, sleep duration, sleep efficiency, and sleep arousal can be assessed.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Exercise test - Steep Ramp Test

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  13-14 years
     
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    The Steep Ramp Test is a short maximal exercise test that measures the peak work rate (WRpeak), which is a valid and reliable estimation of the maximal aerobic exercise capacity and thus cardiorespiratory fitness.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Audiometry

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  9-10 years 13-14 years 17-18 years
     
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    Audiometry measurements evaluate an individual's hearing abilities, with pure-tone audiometry assessing hearing sensitivity across different frequencies and intensities, and tympanometry measuring the middle ear's response to changes in air pressure.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 years
     
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    A blood sample consists of taking an amount of a person's blood from their body.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood pressure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    Blood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Hair sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years
     
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    A hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Eye examination

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
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    The eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Intima-media thickness

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  9-10 years 13-14 years
     
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    Thickness of the carotid intima media was assessed through ultrasonographic recordings.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Saliva sample - Testosterone

    Study:L-CID
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Middle Childhood Cohort  MCC - T5
     
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    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Saliva sample - Dehydroepiandrosterone (DHEA)

    Study:L-CID
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Early Childhood Cohort  ECC - T5

    Middle Childhood Cohort  MCC - T1 MCC - T3 MCC - T5
     
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    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Sleep patterns - Actigraph

    Study:L-CID
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Early Childhood Cohort  ECC - T1 ECC - T2 ECC - T3 ECC - T5 ECC - T6

    Middle Childhood Cohort  MCC - T1 MCC - T2 MCC - T3 MCC - T5
     
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    The Actigraph (Motionlogger) is a device used to determine the sleep patterns of a child during the night.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Urinary osmolality

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Urinary osmolality was measured with a density test (specific gravity) using the Atago refractometer PAL-10S BLT/A+W (Atago, Tokyo, Japan). The refractive index is a ratio of the velocity of light in air to the velocity of light in solution, which is directly proportional to the number of dissolved solids in urine.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Buccal swab

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3 YC_BS1 YC_BS2 YC_BS3 YC_DSC YE_FITNSS YE_ATTEF1 YE_ATTEF2 YE_ATTEF3 YC_ADHMRI YE_COG18
     
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    Buccal swabs are collections of buccal cell scrapings obtained by rubbing buds along the inside of the mouth.
    Created June 5, 2024 • Updated June 20, 2024

  • measure LC-MS amines

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Neuropeptides

    Study:Netherlands Twin Register
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Young Netherlands Twin Register  YC_ACTION BB1_1 YC_ACTION BB1_2 YC_ACTION BB2 YC_ACTION - BB3
     
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    Neuropeptides, including Substance P, Beta-endorphin, Dynorphin A, neurotensin, and Leu-enkaphalin, were measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024
You can also access this registry using the API (see API Docs).