-
measure Airway inflammation and airway resistance
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 yearsAirway interrupter resistance (Rint) was measured in kilo-pascals per liter during tidal expiration, with occlusion of the airway at peak expiratory flow. Fractional exhaled nitric oxide (FeNO) in parts per billion (ppb) was measured using the NIOX chemiluminescence analyzer.Created October 17, 2024 • Updated October 20, 2024 -
measure Heart ultrasound
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 5-6 yearsHeart ultrasound, also known as echocardiography, is a non-invasive medical imaging technique that uses sound waves to create real-time images of the heart's structures, chambers, valves, and blood flow, providing information about its functioning and potential abnormalities.Created October 17, 2024 • Updated October 20, 2024 -
measure Blood sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 yearsA blood sample consists of taking an amount of a person's blood from their body.Created October 17, 2024 • Updated October 20, 2024 -
measure Glucose metabolism
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Birth 5-6 yearsBlood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Raven's Progressive Matrices Test (RPM) - set I
Study: Generation R Mode of collection: MeasurementsAndTests Behavioral/cognitive task Available measurements: Generation R 5-6 yearsRaven's Progressive Matrices (often referred to simply as Raven's Matrices or RPM) is a non-verbal test used to measure general intelligence and abstract reasoning. It is one of the most common tests administered to both groups and individuals ranging from 5-years-olds to the elderly. It consists of 60 multiple choice questions, listed in order of...Created October 17, 2024 • Updated October 20, 2024 -
measure PROP taster status
Study: Generation R Mode of collection: MeasurementsAndTests Behavioral/cognitive task Available measurements: Generation R 5-6 yearsPROP taster status was determined by using a method developed by Keller et al. (2002). Children were classified as "tasters" or "non-tasters" by giving them 5 ml of 0.56 mmol l-1 solution of PROP (6-n-propylthiouracil; pharmacy of Erasmus MC, Rotterdam, The Netherlands) after which they were asked the question: "Do you taste anything?"Created October 17, 2024 • Updated October 20, 2024 -
measure Height and weight
Study: Generation R Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 yearsHeight and weight were measured without shoes and heavy clothing.Created October 17, 2024 • Updated October 20, 2024 -
measure Blood pressure
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 yearsBlood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...Created October 17, 2024 • Updated October 20, 2024 -
measure Nasal and nasalpharyngeal swab
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 yearsNasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.Created October 17, 2024 • Updated October 20, 2024 -
measure Abdominal fat mass
Study: Generation R Mode of collection: MeasurementsAndTests Echo Available measurements: Generation R 2 years 5-6 years 13-14 yearsMeasures of abdominal fat mass were estimated by ultrasound.Created October 17, 2024 • Updated October 20, 2024 -
measure Hair sample
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 yearsA hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.Created October 17, 2024 • Updated October 20, 2024 -
measure Snijders-Oomen Niet-verbale Intelligentie Test 2.5-7 jaar revisie (SON-R 2.5-7)
Study: Generation R Mode of collection: MeasurementsAndTests Behavioral/cognitive task Available measurements: Generation R 5-6 yearsThe Snijders-Oomen Niet-verbale Intelligentie Test 2.5-7 jaar revisie (SON-R 2.5-7) is a test battery that assesses intelligence in young children without the need to use language. It consists of the subtest puzzles, categories, patterns, situations, mosaics and analogies, which together assess abstract reasoning and spatial insight abilities.Created October 17, 2024 • Updated October 20, 2024 -
measure Arterial stiffness
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 yearsArterial stiffness was measured directly via carotid–femoral pulse‐wave velocity (PWV) and indirectly using pulse pressure (PP).Created October 17, 2024 • Updated October 20, 2024 -
measure Diffusion Tensor Imaging (DTI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 7 years 9-10 years 13-14 years 17-18 yearsDiffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.Created October 17, 2024 • Updated October 20, 2024 -
measure Inflammation and immunology markers
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy Mid pregnancy 5-6 years 9-10 yearsInflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Eye examination
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R 5-6 years 9-10 years 13-14 years 17-18 yearsThe eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.Created October 17, 2024 • Updated October 20, 2024 -
measure Metabolic biomarkers
Study: Generation R Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Generation R Early pregnancy 5-6 years 9-10 yearsLipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 7 years 9-10 years 13-14 years 17-18 yearsFunctional magnetic resonance imaging (MRI) is a non-invasive technique for examining brain activity. Resting state fMRI aims to assess spontaneous brain activity using MRI while the participant is at rest, not performing any specific task. It captures ongoing functional connectivity patterns within the brain.Created October 17, 2024 • Updated October 20, 2024 -
measure Neuropsychological development (NEPSY-II-NL)
Study: Generation R Mode of collection: MeasurementsAndTests Behavioral/cognitive task Available measurements: Generation R 7 yearsThe NEPSY-II-NL is a Dutch adaptation of the NEPSY-II which assesses neuropsychological functioning. The test battery consists of 34 subtests that assess four domains: Attention and executive functions, Language, Memory and learning, Sensorimotoric integration, Social cognition, and Visuospatial processing.Created October 17, 2024 • Updated October 20, 2024 -
measure Dental caries and developmental defect of enamel
Study: Generation R Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Generation R 5-6 years 13-14 years 17-18 yearsIntra-oral photographs were made using an intra-oral camera, and were scored for dental caries and developmental defects of enamel by dentists.Created October 17, 2024 • Updated October 20, 2024