• measure Body composition and bone mineral density (Dual X energy absorptiometry)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
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    Dual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Urine sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 years
     
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    30
    years
    First-morning, spot, or 24 hour urine sample.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Airway inflammation and airway resistance

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years
     
    0
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    years
    Airway interrupter resistance (Rint) was measured in kilo-pascals per liter during tidal expiration, with occlusion of the airway at peak expiratory flow. Fractional exhaled nitric oxide (FeNO) in parts per billion (ppb) was measured using the NIOX chemiluminescence analyzer.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Heart ultrasound

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  5-6 years
     
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    years
    Heart ultrasound, also known as echocardiography, is a non-invasive medical imaging technique that uses sound waves to create real-time images of the heart's structures, chambers, valves, and blood flow, providing information about its functioning and potential abnormalities.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 years
     
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    30
    years
    A blood sample consists of taking an amount of a person's blood from their body.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Glucose metabolism

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 5-6 years
     
    0
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    30
    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Height and weight

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    30
    years
    Height and weight were measured without shoes and heavy clothing.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood pressure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    years
    Blood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Nasal and nasalpharyngeal swab

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 years
     
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    Nasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Abdominal fat mass

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  2 years 5-6 years 13-14 years
     
    0
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    years
    Measures of abdominal fat mass were estimated by ultrasound.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Hair sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years
     
    0
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    10
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    30
    years
    A hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Arterial stiffness

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years
     
    0
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    years
    Arterial stiffness was measured directly via carotid–femoral pulse‐wave velocity (PWV) and indirectly using pulse pressure (PP).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Diffusion Tensor Imaging (DTI)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Generation R  7 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
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    20
    25
    30
    years
    Diffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Inflammation and immunology markers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy 5-6 years 9-10 years
     
    0
    5
    10
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    30
    years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Eye examination

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
    0
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    years
    The eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Metabolic biomarkers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy 5-6 years 9-10 years
     
    0
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    30
    years
    Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Generation R  7 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
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    25
    30
    years
    Functional magnetic resonance imaging (MRI) is a non-invasive technique for examining brain activity. Resting state fMRI aims to assess spontaneous brain activity using MRI while the participant is at rest, not performing any specific task. It captures ongoing functional connectivity patterns within the brain.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Dental caries and developmental defect of enamel

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  5-6 years 13-14 years 17-18 years
     
    0
    5
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    30
    years
    Intra-oral photographs were made using an intra-oral camera, and were scored for dental caries and developmental defects of enamel by dentists.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Biomarkers in endocrinology/nephrology

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy 5-6 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Saliva sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created June 5, 2024 • Updated September 19, 2024
You can also access this registry using the API (see API Docs).