• measure Genotyping array and DNA exome array

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    Assessment of single nucleotide polymorphisms (SNPs) as obtained through genotyping arrays.
    Created June 5, 2024 • Updated September 19, 2024

  • measure LC-MS lipids

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Genotyping (array)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    Assessment of micro-satellite markers, single nucleotide polymorphisms (SNP), and variable number (short) tandem repeats (VNTRs) as obtained through genotyping arrays.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Cordblood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    A cordblood sample consists of taking an amount of a person's blood from their umbilical cord. The umbilical cord is the rope-like structure that connects a mother to her unborn baby. After the cord is cut, a health care provider will use a tool called a clamp to stop the cord from bleeding. The provider will then use a needle to withdraw blood from the...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    A blood sample consists of taking an amount of a person's blood from their body.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Glucose metabolism

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 5-6 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure LC-MS amino acids and carnitines

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created June 5, 2024 • Updated September 19, 2024

  • measure DNA methylation (candidate genes)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    DNA methylation of selected candidate genes, such as Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT).
    Created June 5, 2024 • Updated September 19, 2024

  • measure DNA methylation (array)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Birth
     
    0
    5
    10
    15
    20
    25
    30
    years
    Assessment of DNA methylation as obtained through DNA methylation arrays.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Inflammation and immunology markers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy 5-6 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Metabolic biomarkers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy 5-6 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Saliva sample - Cortisol

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  1 year
     
    0
    5
    10
    15
    20
    25
    30
    years
    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Biomarkers in endocrinology/nephrology

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy 5-6 years 9-10 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Liver enzymes, for instance Albumin, Jodide, Aspartaat Aminotransferase (ASAT), and Alanine Transaminase (ALAT), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Saliva sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years
     
    0
    5
    10
    15
    20
    25
    30
    years
    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Viral infections - Herpes Simplex Virus 1 (HSV-1)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Blood sugar markers - Insulin

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Buccal swab

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3

    The Next Generation  NEXT - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Buccal swabs are collections of buccal cell scrapings obtained by rubbing buds along the inside of the mouth.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Peptide hormones - Adrenocorticotropic Hormone (ACTH)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Peptide hormones, for instance Adrenocorticotropic Hormone (ACTH, pituitary hormone), Alpha-Melanocyte-Stimulating Hormone (α-MSH, Melanocortin), Luteinizing Hormone (LH), Cholecytokinin, and Follicle Stimulating Hormone (FSH), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Saliva sample

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T1

    Clinical cohort  CC - T1
     
    0
    5
    10
    15
    20
    25
    30
    years
    Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Lipids - Cholesterol

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024
You can also access this registry using the API (see API Docs).