• measure Lung function - Spirometry

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  9-10 years 13-14 years
     
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    Lung function was measured by spirometry. Measures included FEV1, forced vital capacity (FVC), FEV1/FVC ratio, and forced expiratory flow at 75% of FVC (FEF75).
    Created October 17, 2024 • Updated October 20, 2024

  • measure LC-MS lipids

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 9-10 years
     
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    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting lipid species.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Body composition and bone mineral density (Dual X energy absorptiometry)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
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    Dual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Lungs - Allergy test

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  9-10 years
     
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    Sensitization for birch, cat or dog, or five grass mixture was measured with skin prick tests. Allergy outcomes were categorized into the groups “no inhalant allergic sensitization, no physician-diagnosed inhalant allergy,” “inhalant allergic sensitization but no physician-diagnosed inhalant allergy,” “no inhalant allergic sensitization but...
    Created October 17, 2024 • Updated October 20, 2024

  • measure Urine sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 years
     
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    years
    First-morning, spot, or 24 hour urine sample.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Actigraphy

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  12 years
     
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    Actigraphy estimates children's sleep on both week and weekend days by wearing a tri-axial wrist accelerometer (GENEActiv, Activinsights, UK) for 9 subsequent days on their non-dominant wrist. From the actigraph, sleep duration, sleep efficiency, and sleep arousal can be assessed.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Cardiac measurements - Magnetic Resonance Imaging

    Study:Generation R
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Generation R  9-10 years
     
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    Magnetic Resonance Imaging (MRI) scans were made to assess cardiac structure, diastolic volume, systolic volume, functional cardiac measurements, ejection fraction, stroke volume and aortic diameter.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Dental development

    Study:Generation R
    Mode of collection: MeasurementsAndTests    X-ray
    Available measurements:
    Generation R  9-10 years 13-14 years
     
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    Panoramic radiographs were used to ascertain dental development.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Cardiac and renal structure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Echo
    Available measurements:
    Generation R  6 weeks 6 months 2 years 9-10 years
     
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    Ultrasound measurements were performed to obtain measures of cardiac and renal structure.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Blood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 years
     
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    years
    A blood sample consists of taking an amount of a person's blood from their body.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Height and weight

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Anthropometrics/Body measures
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 2 months 3 months 4 months 6 months 1 year 1.5 years 2 years 2.5 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    years
    Height and weight were measured without shoes and heavy clothing.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Blood pressure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    years
    Blood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...
    Created October 17, 2024 • Updated October 20, 2024

  • measure Nasal and nasalpharyngeal swab

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  6 weeks 6 months 1 year 2 years 3 years 5-6 years 9-10 years
     
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    Nasal and nasalpharyngeal samples were taken by the use of swabs that were rubbed through the nostrils and the upper part of the throat located behind the nasal cavity. Colonization with Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis was determined afterwards.
    Created October 17, 2024 • Updated October 20, 2024

  • measure LC-MS amino acids and carnitines

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Birth 9-10 years
     
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    years
    Liquid chromatography mass spectrometry (LC-MS) platform targeting amines.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Hair sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years
     
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    years
    A hair sample is a collection of hair strands, which are usually cut from a person's head. Hair samples usually contain hair that has grown over the last 12 months.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Diffusion Tensor Imaging (DTI)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Generation R  7 years 9-10 years 13-14 years 17-18 years
     
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    years
    Diffusion Tensor Imaging (DTI) is a Magnetic Resonance Imaging‑based neuroimaging technique that makes it possible to estimate the location, orientation, and anisotropy of the white matter tracts of the brain.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Inflammation and immunology markers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy 5-6 years 9-10 years
     
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    years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Eye examination

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
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    years
    The eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.
    Created October 17, 2024 • Updated October 20, 2024

  • measure Metabolic biomarkers

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy 5-6 years 9-10 years
     
    0
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    30
    years
    Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created October 17, 2024 • Updated October 20, 2024

  • measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    MRI
    Available measurements:
    Generation R  7 years 9-10 years 13-14 years 17-18 years
     
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    years
    Functional magnetic resonance imaging (MRI) is a non-invasive technique for examining brain activity. Resting state fMRI aims to assess spontaneous brain activity using MRI while the participant is at rest, not performing any specific task. It captures ongoing functional connectivity patterns within the brain.
    Created October 17, 2024 • Updated October 20, 2024
You can also access this registry using the API (see API Docs).