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measure Functional connectivity Magnetic Resonance Imaging (rs-fMRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 7 years 9-10 years 13-14 years 17-18 yearsFunctional magnetic resonance imaging (MRI) is a non-invasive technique for examining brain activity. Resting state fMRI aims to assess spontaneous brain activity using MRI while the participant is at rest, not performing any specific task. It captures ongoing functional connectivity patterns within the brain.Created October 17, 2024 • Updated October 20, 2024 -
measure Dental caries and developmental defect of enamel
Study: Generation R Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Generation R 5-6 years 13-14 years 17-18 yearsIntra-oral photographs were made using an intra-oral camera, and were scored for dental caries and developmental defects of enamel by dentists.Created October 17, 2024 • Updated October 20, 2024 -
measure Electroencephalography (EEG) - Go-No Go task
Study: Generation R Mode of collection: MeasurementsAndTests EEG Behavioral/cognitive task Available measurements: Generation R 17-18 yearsElectrocardiography (EEG) was measured while participants performed a Go-No Go task to measure inhibitory control and error processing.Created October 17, 2024 • Updated October 20, 2024 -
measure Structural Magnetic Resonance Imaging (MRI)
Study: Generation R Mode of collection: MeasurementsAndTests MRI Available measurements: Generation R 7 years 9-10 years 13-14 years 17-18 yearsStructural magnetic resonance imaging (MRI) is a non-invasive technique for examining the anatomy and pathology of the brain (as opposed to using functional magnetic resonance imaging [fMRI] to examine brain activity).Created October 17, 2024 • Updated October 20, 2024 -
measure Steroid hormones
Study: RADAR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Cohort RY - W3 RY - W4 RY - W5Steroid hormones, for instance Testosterone, Estrogen, Dehydroepiandrosterone (DHEA), and Cortisol, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Leiden Public Speaking Task
Study: RADAR Mode of collection: MeasurementsAndTests Behavioral/cognitive task ECG Biological sample/measurement Available measurements: Young Cohort RY - W5 RY - W6The Leiden Public Speaking Task assesses physiological reactivity to social evaluation threat. The task contains five phases: baseline (of which 5 minutes standing, 15 minutes after start of the baseline), anticipation (3 mins), preparation (5 mins), speech delivery (5 mins), and recovery (of which 5 mins standing, approximately 10 mins after the end of...Created October 17, 2024 • Updated October 20, 2024 -
measure Saliva Sample
Study: RADAR Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Young Cohort RY - W5 RY - W10Saliva was collected using a cotton swab or a collection device, such as a tube or container (passive drool).Created October 17, 2024 • Updated October 20, 2024 -
measure Viral infections - Herpes Simplex Virus 1 (HSV-1)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Blood sugar markers - Insulin
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Buccal swab
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3
The Next Generation NEXT - T3Buccal swabs are collections of buccal cell scrapings obtained by rubbing buds along the inside of the mouth.Created October 17, 2024 • Updated October 20, 2024 -
measure Eyeblink reflex
Study: TRAILS Mode of collection: MeasurementsAndTests EMG Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Eyeblink reflexes were assessed using electromyography (EMG), both at rest and during the Startle Reflex Task.Created October 17, 2024 • Updated October 20, 2024 -
measure Waist and hip circumference
Study: TRAILS Mode of collection: MeasurementsAndTests Anthropometrics/Body measures Available measurements: Population cohort POP - T3 POP - T4 POP - T5
Clinical cohort CC - T3 CC - T4 CC - T5Waist and hip circumference were assessed using a tape measure.Created October 17, 2024 • Updated October 20, 2024 -
measure Respiratory Sinus Arrhythmia (RSA)
Study: TRAILS Mode of collection: MeasurementsAndTests ECG Available measurements: Population cohort POP - T1 POP - T3
Clinical cohort CC - T1 CC - T3Respiratory sinus arrhythmia is part of the autonomic nervous system and serves to optimize gas exchange between the lungs and the circulatory system. It was measured through an electrocardiogram (ECG) and included respiratory sinus arrhythmia at rest, during orthostatic stress, and during the Spatial Orienting Task and Bangor Gambling Task.Created October 17, 2024 • Updated October 20, 2024 -
measure Peptide hormones - Adrenocorticotropic Hormone (ACTH)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Peptide hormones, for instance Adrenocorticotropic Hormone (ACTH, pituitary hormone), Alpha-Melanocyte-Stimulating Hormone (α-MSH, Melanocortin), Luteinizing Hormone (LH), Cholecytokinin, and Follicle Stimulating Hormone (FSH), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Lipids - Cholesterol
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Baroreflex Sensitivity (BRS)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T1 POP - T3
Clinical cohort CC - T1 CC - T3Baroreflex Sensitivity (BRS) assessment using an electrocardiogram (ECG). The baroreflex is part of the autonomic nervous system and helps to maintain the blood pressure at a constant level. Measurements include baroreflex sensitivity at rest, during orthostatic stress, and during the Spatial Orienting Task and Bangor Gambling Task.Created October 17, 2024 • Updated October 20, 2024 -
measure Inflammation markers - C-reactive Protein (CRP)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Blood sugar markers - Glucose
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024 -
measure Pubertal Development Scale (PDS)
Study: TRAILS Mode of collection: SelfAdministeredQuestionnaire Available measurements: Population cohort POP - T2 POP - T3
Clinical cohort CC - T2 CC - T3The Pubertal Development Scale (PDS) assesses the development of secondary sexual characteristics, such as growth spurts, body hair growth, skin changes, breast development and menarche in girls, and voice changes and growth of testes in boys.Created October 17, 2024 • Updated October 20, 2024 -
measure Viral infections - Epstein-Barr Virus (EBV)
Study: TRAILS Mode of collection: MeasurementsAndTests Biological sample/measurement Available measurements: Population cohort POP - T3
Clinical cohort CC - T3Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).Created October 17, 2024 • Updated October 20, 2024