• measure Body composition and bone mineral density (Dual X energy absorptiometry)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
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    years
    Dual X energy absorptiometry scans (iDXA; General Electric, formerly Lunar Corp., Madison, WI) were used to obtain measurements of bone and soft tissue for the total body and sub regions, including bone mineral content (g), fat mass (g), and lean mass (g).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Dental plaque and oral microbiome

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  13-14 years 17-18 years
     
    0
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    30
    years
    Dental plaque samples were collected by rubbing a cotton swab over the buccal sides of the right lower permanent molars. DNA was isolated from the dental plaque swabs.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Bone mineral density and geometry of the tibia (Peripheral Quantitative Compu...

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  13-14 years 17-18 years
     
    0
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    25
    30
    years
    Measurements of bone mineral density and the Geometry of the tibia by peripheral quantitative computed tomography (CT).
    Created June 5, 2024 • Updated September 19, 2024

  • measure Urine sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 5-6 years 9-10 years 13-14 years 17-18 years
     
    0
    5
    10
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    30
    years
    First-morning, spot, or 24 hour urine sample.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Muscle function and bone strength (Mechanography)

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  17-18 years
     
    0
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    30
    years
    Muscle function and bone strength were assessed using mechanography. This includes a mechanographic record of jumping movements on a specially designed springboard. Relevant functional parameters such as strength and spot force are measured to determine coordination, muscle function and muscle-bone relationship.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Audiometry

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  9-10 years 13-14 years 17-18 years
     
    0
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    30
    years
    Audiometry measurements evaluate an individual's hearing abilities, with pure-tone audiometry assessing hearing sensitivity across different frequencies and intensities, and tympanometry measuring the middle ear's response to changes in air pressure.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood sample

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Birth 6 months 1 year 1.5 years 2 years 3 years 5-6 years 8 years 9-10 years 13-14 years 17-18 years
     
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    years
    A blood sample consists of taking an amount of a person's blood from their body.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Blood pressure

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  Early pregnancy Mid pregnancy Late pregnancy 6 weeks 6 months 1 year 2 years 3 years 4 years 5-6 years 9-10 years 13-14 years 17-18 years
     
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    30
    years
    Blood pressure is the force of blood pushing against the walls of arteries as the heart pumps blood around the body. Systolic pressure is the pressure when the heart contracts and pushes blood out and diastolic pressure is the pressure when the heart relaxes and fills with blood. In adults, the systolic pressure normally ranges between 80 and 120 and the...
    Created June 5, 2024 • Updated September 19, 2024

  • measure Eye examination

    Study:Generation R
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Generation R  5-6 years 9-10 years 13-14 years 17-18 years
     
    0
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    years
    The eye examination is a visual acuity test. The eye examination consisted of presenting monocular visual acuity with logarithm of the minimum angle of resolution based Early Treatment Diabetic Retinopathy Study charts at 3 m by means of the fast Early Treatment Diabetic Retinopathy Study method.
    Created June 5, 2024 • Updated September 19, 2024

  • measure Viral infections - Herpes Simplex Virus 1 (HSV-1)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Blood sugar markers - Insulin

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Buccal swab

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3

    The Next Generation  NEXT - T3
     
    0
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    30
    years
    Buccal swabs are collections of buccal cell scrapings obtained by rubbing buds along the inside of the mouth.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Shuttle run test

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
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    25
    30
    years
    The shuttle run test is a validated assessment of physcial fitness. In the task, participants have to continuously run between two lines that are twenty meters apart and reach the lines before a recorded beep. Measurements include performance, heart rate, heart rate variability, and lung capacity.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Startle Reflex Task

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Behavioral/cognitive task Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
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    25
    30
    years
    The Startle Reflex Task is an assessment of physiological and subjective stress reactivity. In the task, participants have to watch nine short videos: 3 videos for habituation, 2 positive, 2 neutral and 2 unpleasant videos. During the videos, participants are startled by a white noise, and they are instructed to ignore them. After the task, participants...
    Created June 5, 2024 • Updated June 20, 2024

  • measure Peptide hormones - Adrenocorticotropic Hormone (ACTH)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Peptide hormones, for instance Adrenocorticotropic Hormone (ACTH, pituitary hormone), Alpha-Melanocyte-Stimulating Hormone (α-MSH, Melanocortin), Luteinizing Hormone (LH), Cholecytokinin, and Follicle Stimulating Hormone (FSH), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Lipids - Cholesterol

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Baroreflex Sensitivity (BRS)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T1 POP - T3

    Clinical cohort  CC - T1 CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Baroreflex Sensitivity (BRS) assessment using an electrocardiogram (ECG). The baroreflex is part of the autonomic nervous system and helps to maintain the blood pressure at a constant level. Measurements include baroreflex sensitivity at rest, during orthostatic stress, and during the Spatial Orienting Task and Bangor Gambling Task.
    Created June 5, 2024 • Updated June 20, 2024

  • measure Inflammation markers - C-reactive Protein (CRP)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Inflammation markers, for instance C-reactive protein (CRP), Lymphocytes, Neopterin, Immunoglobulin E (IgE), Immunoglobulin G (IgG), and tissue Transglutaminase Immunoglobulin A (tTg-IgA), measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Blood sugar markers - Glucose

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Blood sugar markers, for instance Glucose, Insulin, and C-peptide, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024

  • measure Viral infections - Epstein-Barr Virus (EBV)

    Study:TRAILS
    Mode of collection: MeasurementsAndTests    Biological sample/measurement
    Available measurements:
    Population cohort  POP - T3

    Clinical cohort  CC - T3
     
    0
    5
    10
    15
    20
    25
    30
    years
    Viral and parasitic infection loads, for instance Influenza A, Influenza B, Herpes Simplex Virus 1 (HSV1), Herpes Simplex Virus 2 (HSV2), Toxoplasma Gondii, Cytomegalovirus (CMV), Epstein-Barr Virus (EBV), and Procalcitonin, measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).
    Created June 5, 2024 • Updated June 20, 2024
You can also access this registry using the API (see API Docs).