Lipids - Apolipoproteins (ApoA-1 and ApoB-100)

Lipids, for instance Cholesterol, Triglycerides, Low-Density Lipoprotein Cholesterol (LDL-C), High-Density Lipoprotein Cholesterol (HDL-C), Lipoproteins, and Apolipoproteins measured with traditional enzymatic tests, such as Enzyme-Linked Immunosorbent Assays (ELISA).

In TRAILS, the apolipoproteins Apolipoprotein A 1 (ApoA-1) and Apolipoprotein B 100 (ApoB-100) were assessed, both proteins that bind lipids to form lipoproteins. Because lipids, such as cholesterol and triglycerides, are insoluble in water, these lipids are transported as lipoproteins. ApoA-1 is specifically used to create High-Density Lipoproteins (HDL) and ApoB-100 to create Low-Density Lipoproteins (LDL). HDL is a cardiovascular health marker, while LDL is a cardiovascular problems marker. ApoA-1 and ApoB-100 were assessed in very few participants from their blood sample using traditional enzymatic methods such as Enzyme Immuno Assay (EIA).

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Keywords
Constructs
Waves
  • Population cohort

  • POP - T3
  •   C
    15.0 - 17.0 years   From 2005-09-01 to 2008-08-31

  • Clinical cohort

  • CC - T3
  •   C
    15.0 - 17.0 years   From 2009-09-01 to 2011-02-28

    Mode of collection MeasurementsAndTests    Biological sample/measurement
    Analysis unit Individual
    Instrument name Apolipoproteins (ApoA-1 and ApoB-100)
    Measure name Lipids
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