Structural Magnetic Resonance Imaging (MRI)

Structural magnetic resonance imaging (MRI) is a non-invasive technique for examining the anatomy and pathology of the brain (as opposed to using functional magnetic resonance imaging [fMRI] to examine brain activity).

In L-CID, a high-resolution three-dimensional (3D) T1 MRI scan was performed as an anatomical reference. The imaging parameters used remained constant throughout the waves. The field of view (FOV) for the scan was 224 mm in the anterior-posterior (ap) direction, 177 mm in the right-left (rl) direction, and 168 mm in the foot-head (fh) direction. The imaging parameters used were as follows: repetition time (TR) of 9.72 ms, echo time (TE) of 4.95 ms, and flip angle (FA) of 8°. A total of 140 slices were acquired with a voxel size of 0.875 mm x 0.875 mm x 0.875 mm. The MRI scans were conducted using a Philips Ingenia 3.0 T MRI system, employing a standard whole-head coil. To minimize head motion during the scan, foam inserts were utilized to securely hold the children's heads in place. To ensure a comfortable experience for the participants, they were allowed to watch a child-friendly movie of their choice while undergoing the structural anatomical scan (3DT1).

Citation Loading citation...
Keywords
Constructs
Waves
  • Early Childhood Cohort

  • ECC - T5
    •   C
    7.0 - 9.0 years   From 2019-02-06 to 2019-10-19
  • Middle Childhood Cohort

  • MCC - T1
    •   C
    7.0 - 9.0 years   From 2015-06-16 to 2016-08-27
  • MCC - T3
    •   C
    9.0 - 11.0 years   From 2017-08-27 to 2018-09-30
  • MCC - T5
    •   C
    11.0 - 13.0 years   From 2019-11-04 to 2021-04-28
  • MCC - T7
    •   C
    14.0 - 15.0 years   From 2023-04-01 to 2023-10-30
    Mode of collection MeasurementsAndTests    MRI
    Analysis unit Individual
    Instrument name Structural Magnetic Resonance Imaging
    Measure name MRI - 3DTI
    References
    Achterberg, M., & van der Meulen, M. (2019). Genetic and environmental influences on MRI scan quantity and quality. Developmental Cognitive Neuroscience, 38, 100667. https://doi.org/10.1016/j.dcn.2019.100667
    van der Meulen, M., Wierenga, L. M., Achterberg, M., Drenth, N., van IJzendoorn, M. H., & Crone, E. A. (2020). Genetic and environmental influences on structure of the social brain in childhood. Developmental Cognitive Neuroscience, 44, 100782. https://doi.org/10.1016/j.dcn.2020.100782
    van der Meulen, M., Steinbeis, N., Achterberg, M., van IJzendoorn, M. H., & Crone, E. A. (2018). Heritability of neural reactions to social exclusion and prosocial compensation in middle childhood. Developmental Cognitive Neuroscience, 34, 42–52. https://doi.org/10.1016/j.dcn.2018.05.010
    Achterberg, M., Bakermans-Kranenburg, M. J., van Ijzendoorn, M. H., van der Meulen, M., Tottenham, N., & Crone, E. A. (2018). Distinctive heritability patterns of subcortical-prefrontal cortex resting state connectivity in childhood: A twin study. NeuroImage, 175, 138–149. https://doi.org/10.1016/j.neuroimage.2018.03.076
    Achterberg, M., van Duijvenvoorde, A. C. K., van der Meulen, M., Euser, S., Bakermans-Kranenburg, M. J., & Crone, E. A. (2017). The neural and behavioral correlates of social evaluation in childhood. Developmental Cognitive Neuroscience, 24, 107–117. https://doi.org/10.1016/j.dcn.2017.02.007
    Achterberg, M., van Duijvenvoorde, A. C. K., van der Meulen, M., Bakermans‐Kranenburg, M. J., & Crone, E. A. (2018). Heritability of aggression following social evaluation in middle childhood: An fMRI study. Human Brain Mapping, 39(7), 2828–2841. Portico. https://doi.org/10.1002/hbm.24043
    Achterberg, M., van Duijvenvoorde, A. C. K., van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., & Crone, E. A. (2020). Longitudinal changes in DLPFC activation during childhood are related to decreased aggression following social rejection. Proceedings of the National Academy of Sciences, 117(15), 8602–8610. https://doi.org/10.1073/pnas.1915124117
    van der Meulen, M., Steinbeis, N., Achterberg, M., Bilo, E., van den Bulk, B. G., van IJzendoorn, M. H., & Crone, E. A. (2017). The neural correlates of dealing with social exclusion in childhood. Neuropsychologia, 103, 29–37. https://doi.org/10.1016/j.neuropsychologia.2017.07.008
    van Drunen, L., Dobbelaar, S., van der Cruijsen, R., van der Meulen, M., Achterberg, M., Wierenga, L. M., & Crone, E. A. (2021). The nature of the self: Neural analyses and heritability estimates of self‐evaluations in middle childhood. Human Brain Mapping, 42(17), 5609–5625. Portico. https://doi.org/10.1002/hbm.25641
    You can also access this dataset using the API (see API Docs).