Dataset

DNA methylation (candidate genes)

DNA methylation of selected candidate genes, such as Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT).

In TRAILS, methylation of the Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT) genes was assessed from a blood sample.

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Keywords	omics genomics epigenetics dna catecholamine glucocorticoid receptor gene serotonin transporter gene
Constructs	physiology
Waves	Population cohort POP - T3 C 15.0 - 17.0 years From 2005-09-01 to 2008-08-31 Clinical cohort CC - T3 C 15.0 - 17.0 years From 2009-09-01 to 2011-02-28
Mode of collection	MeasurementsAndTests Biological sample/measurement
Analysis unit	Individual
Instrument name	Candidate gene methylation

Measure was collected within the following cohort study:

TRacking Adolescents' Individual Lives Survey Cohort study

Purpose	The overall purpose of TRAILS is to contribute to the understanding of the determinants of adolescents’ mental (ill-)health and social development during adolescence and young adulthood, as well as the mechanisms underlying the associations between determinants and outcomes.
description
Alternate title	TRAILS
Data access information	A description of how to access TRAILS data can be found on the TRAILS website. Data are released after each assessment wave under specified conditions. https://www.trails.nl/en/hoofdmenu/data/data-use
Publisher	University Medical Center Groningen
Principal investigators	Ormel, Johan University Medical Center Groningen Verhulst, Frank C. Erasmus MC
Cohort study international identifier
Language	NL
Funding information	Dutch Research Council GB-MW 940-38-011 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Medical Research Council program Funder award URI Netherlands Organisation for Health Research and Development 100-001-004 Funder identifier https://ror.org/01yaj9a77 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Brainpower Funder award URI Netherlands Organisation for Health Research and Development 60-60600-97-118 Funder identifier https://ror.org/01yaj9a77 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Risk Behavior and Dependence Funder award URI Netherlands Organisation for Health Research and Development 261-98-710 Funder identifier https://ror.org/01yaj9a77 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Culture and Health Funder award URI Dutch Research Council GB-MaGW 480-01-006 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI Dutch Research Council GB-MaGW 480-07-001 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI Dutch Research Council GB-MaGW 452-04-314 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI Dutch Research Council GB-MaGW 452-06-004 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI Netherlands Organisation for Health Research and Development 636340002 Funder identifier https://ror.org/01yaj9a77 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Longitudinal Cohort Research on Early Detection and Treatment in Mental Health Care Funder award URI Dutch Research Council 175.010.2003.005 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Large-sized investment Funder award URI Dutch Research Council 481-08-013 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI Dutch Research Council 481-11-001 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI Dutch Research Council 016.130.002 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Vici Funder award URI Dutch Research Council 453-16-007/2735 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Vici Funder award URI Dutch Research Council Vi.C 191.021 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Vici Funder award URI Dutch Research Council 024.001.003 Funder identifier https://ror.org/04jsz6e67 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Gravitation Funder award URI European Science Foundation EuroSTRESS project FP-006 Funder identifier https://ror.org/04esata81 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Funder award URI European Research Council ERC-2017-STG-757364 Funder identifier https://ror.org/0472cxd90 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Funder award URI European Research Council ERC-CoG-2015-681466 Funder identifier https://ror.org/0472cxd90 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Funder award URI Biobanking and BioMolecular resources Research Infrastructure The Netherlands CP 32 Funder identifier https://ror.org/0003kpv33 Funder identifier type ROR Funder identifier type URI https://ror.org/ Funder award title Funder award URI
Contact information	Oldehinkel, Albertine J. University Medical Center Groningen a.j.oldehinkel@umcg.nl Hartman, Catharina A. University Medical Center Groningen c.a.hartman@umcg.nl
References	Oldehinkel AJ, Rosmalen JGM, Buitelaar JK, Hoek HW, Ormel J, Raven D, Reijneveld SA, Veenstra R, Verhulst FC, Vollebergh WAM, Hartman CA. Cohort Profile update. The TRacking Adolescents’ Individual Lives Survey (TRAILS)[1]. Int J Epidemiol 2015; 44(1):76-76n. Huisman M, Oldehinkel AJ, De Winter AF, Minderaa RB, De Bildt A, Huizink AC, Verhulst FC, Ormel J. Cohort profile: The Dutch “TRacking Adolescents’ Individual Lives’ Survey”; TRAILS. Int J Epidemiol 2008; 37: 1227-35. Hartman CA, Richards JS, Vrijen C, Oldehinkel AJ, Oerlemans AM, Kretschmer T. Cohort profile update: The Tracking Adolescents’ Individual Lives Survey – The Next Generation (TRAILS NEXT). Int J Epidemiol 2022. De Winter AF, Oldehinkel AJ, Veenstra R, Brunnekreef JA, Verhulst FC, Ormel J. Evaluation of nonresponse bias in mental health determinants and outcomes in a large sample of preadolescents. Eur J Epidemiol 2005; 20:173-81. Nederhof E, Jörg, F, Raven D, Veenstra R, Verhulst FC, Ormel J, Oldehinkel AJ. Benefits of extensive recruitment effort persist during follow-ups and are constant across age and survey method. The TRAILS study. BMC Med Res Methodol 2012; 12:93 Ormel J, Oldehinkel AJ, Sijtsema J, van Oort F, Raven D, Veenstra R, Vollebergh WA, Verhulst FC. The TRacking Adolescents' Individual Lives Survey (TRAILS): design, current status, and selected findings. J Am Acad Child Adolesc Psychiatry 2012; 51(10):1020-36.
Additional info (URL)
Additional information
Contributors	Oldehinkel, Albertine J. University Medical Center Groningen Hartman, Catharina A. University Medical Center Groningen Rosmalen, Judith G.M. University Medical Center Groningen Veenstra, René University of Groningen Stevens, Gonneke J.W.M. Utrecht University Reijneveld, Sijmen A. University Medical Center Groningen Rommelse, Nanda Radboud University Nijmegen Medical Centre Wijbrand Hoek, H. Parnassia Psychiatric Unit Kretschmer, Tina University of Groningen Bültmann, Ute University Medical Center Groningen
Time method	Longitudinal
Universe	Adolescents, young adults, and adults from the general population (Population cohort) as well as with a high-risk profile (Clinical cohort), and their offspring (The Next Generation), selected from urban and rural areas in the North of the Netherlands at the time of the baseline assessment. The largest ethnic group is the Dutch (89.7%).

Measure was collected within the following cohort(s):

TRAILS: Population cohort Cohort

Alternate title	TRAILS: POP
Description	The TRAILS Population Cohort (TRAILS: POP) started in 2000 (N = 2230 at wave 1) and follows adolescents and young adults from the general population from the age of 11 onwards to study their psychological, social, and physical development. Participants, but also their parents, teachers, peers, and partners, are assessed every 2 to 3 years, through questionnaires, interviews, tests, and physical measurements. Participants were included if they lived in one of the five selected municipalities in Groningen, Friesland and Drenthe (the Netherlands), were born between October 1989 and September 1991, and attended a primary school that agreed to participate at the time.
Purpose	During adolescence and young adulthood, people go through profound changes, both physically and psychologically. These changes affect the way they interact with others, and how they process and cope with their experiences. The choices made and directions taken in these phases of life can have a major impact on future well-being, behavior and health, and even affect the next generation. More knowledge of the causes of a favorable or unfavorable development can help to prevent problems or treat them at an early stage. Not only problematic developmental trajectories are of interest, but successful ones as well.
Publisher	University Medical Center Groningen
Creators	Ormel, Johan University Medical Center Groningen Verhulst, Frank C. Erasmus MC
Language	NL
Cohort international identifier
Funding information	Dutch Research Council GB-MW 940-38-011 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Medical Research Council program Funder award URI Netherlands Organisation for Health Research and Development 100-001-004 Funder identifier https://ror.org/01yaj9a77 ROR Identifier type URI https://ror.org/ Funder award title Brainpower Funder award URI Netherlands Organisation for Health Research and Development 60-60600-97-118 Funder identifier https://ror.org/01yaj9a77 ROR Identifier type URI https://ror.org/ Funder award title Risk Behavior and Dependence Funder award URI Netherlands Organisation for Health Research and Development 261-98-710 Funder identifier https://ror.org/01yaj9a77 ROR Identifier type URI https://ror.org/ Funder award title Culture and Health Funder award URI Dutch Research Council GB-MaGW 480-01-006 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI Dutch Research Council GB-MaGW 480-07-001 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI Dutch Research Council GB-MaGW 452-04-314 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI Dutch Research Council GB-MaGW 452-06-004 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI Netherlands Organisation for Health Research and Development 636340002 Funder identifier https://ror.org/01yaj9a77 ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Cohort Research on Early Detection and Treatment in Mental Health Care Funder award URI Dutch Research Council 175.010.2003.005 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Large-sized investment Funder award URI Dutch Research Council 481-08-013 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI Dutch Research Council 481-11-001 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI Dutch Research Council 016.130.002 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI Dutch Research Council 453-16-007/2735 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI Dutch Research Council Vi.C 191.021 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI Dutch Research Council 024.001.003 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Gravitation Funder award URI European Science Foundation EuroSTRESS project FP-006 Funder identifier https://ror.org/04esata81 ROR Identifier type URI https://ror.org/ Funder award title Funder award URI European Research Council ERC-2017-STG-757364 Funder identifier https://ror.org/0472cxd90 ROR Identifier type URI https://ror.org/ Funder award title Funder award URI European Research Council ERC-CoG-2015-681466 Funder identifier https://ror.org/0472cxd90 ROR Identifier type URI https://ror.org/ Funder award title Funder award URI Biobanking and BioMolecular resources Research Infrastructure The Netherlands CP 32 Funder identifier https://ror.org/0003kpv33 ROR Identifier type URI https://ror.org/ Funder award title Funder award URI
Cohort reference papers
Classification
Contact information
Waves
Contributors	Oldehinkel, Albertine J. University Medical Center Groningen Hartman, Catharina A. University Medical Center Groningen Rosmalen, Judith G.M. University Medical Center Groningen Veenstra, René University of Groningen Stevens, Gonneke J.W.M. Utrecht University Reijneveld, Sijmen A. University Medical Center Groningen Rommelse, Nanda Radboud University Nijmegen Medical Centre Wijbrand Hoek, H. Parnassia Psychiatric Unit Kretschmer, Tina University of Groningen Bültmann, Ute University Medical Center Groningen
References	Oldehinkel AJ, Rosmalen JGM, Buitelaar JK, Hoek HW, Ormel J, Raven D, Reijneveld SA, Veenstra R, Verhulst FC, Vollebergh WAM, Hartman CA. Cohort Profile update. The TRacking Adolescents’ Individual Lives Survey (TRAILS)[1]. Int J Epidemiol 2015; 44(1):76-76n. Huisman M, Oldehinkel AJ, De Winter AF, Minderaa RB, De Bildt A, Huizink AC, Verhulst FC, Ormel J. Cohort profile: The Dutch “TRacking Adolescents’ Individual Lives’ Survey”; TRAILS. Int J Epidemiol 2008; 37: 1227-35. De Winter AF, Oldehinkel AJ, Veenstra R, Brunnekreef JA, Verhulst FC, Ormel J. Evaluation of nonresponse bias in mental health determinants and outcomes in a large sample of preadolescents. Eur J Epidemiol 2005; 20:173-81. Nederhof E, Jörg, F, Raven D, Veenstra R, Verhulst FC, Ormel J, Oldehinkel AJ. Benefits of extensive recruitment effort persist during follow-ups and are constant across age and survey method. The TRAILS study. BMC Med Res Methodol 2012; 12:93 Ormel J, Oldehinkel AJ, Sijtsema J, van Oort F, Raven D, Veenstra R, Vollebergh WA, Verhulst FC. The TRacking Adolescents' Individual Lives Survey (TRAILS): design, current status, and selected findings. J Am Acad Child Adolesc Psychiatry 2012; 51(10):1020-36.
Country code	NL
Geographic location	Groningen,Drenthe,Friesland
Lowest geographic reference
Highest geographic reference
Cohort universe description	Individuals aged 10-30 years old from the North of the Netherlands.
Analysis unit
Additional info (URL)
Additional information
Time method	Longitudinal.CohortEventBased

TRAILS: Clinical cohort Cohort

Alternate title	TRAILS: CC
Description	The TRAILS Population Cohort (TRAILS: POP) started in 2000 (N = 2230 at wave 1) and follows adolescents and young adults from the general population from the age of 11 onwards to study their psychological, social, and physical development. Participants, but also their parents, teachers, peers, and partners, are assessed every 2 to 3 years, through questionnaires, interviews, tests, and physical measurements. Participants were included if they lived in one of the five selected municipalities in Groningen, Friesland and Drenthe (the Netherlands), were born between October 1989 and September 1991, and attended a primary school that agreed to participate at the time.
Purpose	During adolescence and young adulthood, people go through profound changes, both physically and psychologically. These changes affect the way they interact with others, and how they process and cope with their experiences. The choices made and directions taken in these phases of life can have a major impact on future well-being, behavior and health, and even affect the next generation. More knowledge of the causes of a favorable or unfavorable development can help to prevent problems or treat them at an early stage. Not only problematic developmental trajectories are of interest, but successful ones as well.
Publisher	University Medical Center Groningen
Creators	Ormel, Johan University Medical Center Groningen Verhulst, Frank C. Erasmus MC
Language	NL
Cohort international identifier
Funding information	Dutch Research Council GB-MW 940-38-011 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Medical Research Council program Funder award URI Netherlands Organisation for Health Research and Development 100-001-004 Funder identifier https://ror.org/01yaj9a77 ROR Identifier type URI https://ror.org/ Funder award title Brainpower Funder award URI Netherlands Organisation for Health Research and Development 60-60600-97-118 Funder identifier https://ror.org/01yaj9a77 ROR Identifier type URI https://ror.org/ Funder award title Risk Behavior and Dependence Funder award URI Netherlands Organisation for Health Research and Development 261-98-710 Funder identifier https://ror.org/01yaj9a77 ROR Identifier type URI https://ror.org/ Funder award title Culture and Health Funder award URI Dutch Research Council GB-MaGW 480-01-006 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI Dutch Research Council GB-MaGW 480-07-001 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI Dutch Research Council GB-MaGW 452-04-314 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI Dutch Research Council GB-MaGW 452-06-004 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI Netherlands Organisation for Health Research and Development 636340002 Funder identifier https://ror.org/01yaj9a77 ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Cohort Research on Early Detection and Treatment in Mental Health Care Funder award URI Dutch Research Council 175.010.2003.005 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Large-sized investment Funder award URI Dutch Research Council 481-08-013 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI Dutch Research Council 481-11-001 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI Dutch Research Council 016.130.002 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI Dutch Research Council 453-16-007/2735 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI Dutch Research Council Vi.C 191.021 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI Dutch Research Council 024.001.003 Funder identifier https://ror.org/04jsz6e67 ROR Identifier type URI https://ror.org/ Funder award title Gravitation Funder award URI European Science Foundation EuroSTRESS project FP-006 Funder identifier https://ror.org/04esata81 ROR Identifier type URI https://ror.org/ Funder award title Funder award URI European Research Council ERC-2017-STG-757364 Funder identifier https://ror.org/0472cxd90 ROR Identifier type URI https://ror.org/ Funder award title Funder award URI European Research Council ERC-CoG-2015-681466 Funder identifier https://ror.org/0472cxd90 ROR Identifier type URI https://ror.org/ Funder award title Funder award URI Biobanking and BioMolecular resources Research Infrastructure The Netherlands CP 32 Funder identifier https://ror.org/0003kpv33 ROR Identifier type URI https://ror.org/ Funder award title Funder award URI
Cohort reference papers
Classification
Contact information
Waves
Contributors	Oldehinkel, Albertine J. University Medical Center Groningen Hartman, Catharina A. University Medical Center Groningen Rosmalen, Judith G.M. University Medical Center Groningen Veenstra, René University of Groningen Stevens, Gonneke J.W.M. Utrecht University Reijneveld, Sijmen A. University Medical Center Groningen Rommelse, Nanda Radboud University Nijmegen Medical Centre Wijbrand Hoek, H. Parnassia Psychiatric Unit Kretschmer, Tina University of Groningen Bültmann, Ute University Medical Center Groningen
References	Oldehinkel AJ, Rosmalen JGM, Buitelaar JK, Hoek HW, Ormel J, Raven D, Reijneveld SA, Veenstra R, Verhulst FC, Vollebergh WAM, Hartman CA. Cohort Profile update. The TRacking Adolescents’ Individual Lives Survey (TRAILS)[1]. Int J Epidemiol 2015; 44(1):76-76n. Huisman M, Oldehinkel AJ, De Winter AF, Minderaa RB, De Bildt A, Huizink AC, Verhulst FC, Ormel J. Cohort profile: The Dutch “TRacking Adolescents’ Individual Lives’ Survey”; TRAILS. Int J Epidemiol 2008; 37: 1227-35. De Winter AF, Oldehinkel AJ, Veenstra R, Brunnekreef JA, Verhulst FC, Ormel J. Evaluation of nonresponse bias in mental health determinants and outcomes in a large sample of preadolescents. Eur J Epidemiol 2005; 20:173-81. Nederhof E, Jörg, F, Raven D, Veenstra R, Verhulst FC, Ormel J, Oldehinkel AJ. Benefits of extensive recruitment effort persist during follow-ups and are constant across age and survey method. The TRAILS study. BMC Med Res Methodol 2012; 12:93 Ormel J, Oldehinkel AJ, Sijtsema J, van Oort F, Raven D, Veenstra R, Vollebergh WA, Verhulst FC. The TRacking Adolescents' Individual Lives Survey (TRAILS): design, current status, and selected findings. J Am Acad Child Adolesc Psychiatry 2012; 51(10):1020-36.
Country code	NL
Geographic location	Groningen,Drenthe,Friesland
Lowest geographic reference
Highest geographic reference
Cohort universe description	Individuals aged 10-30 years referred to psychiatric outpatient clinics before the age of 11 in the Northern Netherlands.
Analysis unit
Additional info (URL)
Additional information
Time method	Longitudinal.CohortEventBased

Measure was collected within the following wave(s):

POP - T3 Wave

Wave alternate title	P3, T3
Short description of the wave	The third measurement wave of the TRAILS Population cohort included physical measurements, tasks, registry data, interviews, and biological samples (e.g., blood, buccal sample) measured among 1816 adolescents (52% female), their parents, teachers, and siblings (mean age = 16.3, SD = 0.7).
Type of StudyUnit
Publisher	University Medical Center Groningen
Creators	Ormel, Johan University Medical Center Groningen Verhulst, Frank C. Erasmus MC
Funding information	GB-MW 940-38-011 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Medical Research Council program Funder award URI 100-001-004 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Brainpower Funder award URI 60-60600-97-118 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Risk Behavior and Dependence Funder award URI 261-98-710 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Culture and Health Funder award URI GB-MaGW 480-01-006 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI GB-MaGW 480-07-001 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI GB-MaGW 452-04-314 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI GB-MaGW 452-06-004 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI 636340002 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Cohort Research on Early Detection and Treatment in Mental Health Care Funder award URI 175.010.2003.005 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Large-sized investment Funder award URI 481-08-013 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI 481-11-001 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI 016.130.002 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI 453-16-007/2735 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI Vi.C 191.021 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI 024.001.003 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Gravitation Funder award URI EuroSTRESS project FP-006 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Funder award URI ERC-2017-STG-757364 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Funder award URI ERC-CoG-2015-681466 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Funder award URI CP 32 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Funder award URI
References
(sub) cohort	TRAILS: Population cohort
Life stage
Coverage percentage of the measurement for this wave
Start date wave collection	2005-09-01
End date wave collection	2008-08-31
Wave universe description	15.0 - 17.0 years
Stage of measurement
Language	NL
Description of physical data product	Digital files, biomedical samples
Additional info (URL)	https://doi.org/10.17026/dans-27s-27kw
Additional information	The codebooks for the third wave of the population cohort in TRAILS can be found via DANS.
Contributors	Oldehinkel, Albertine J. University Medical Center Groningen Hartman, Catharina A. University Medical Center Groningen Rosmalen, Judith G.M. University Medical Center Groningen Veenstra, René University of Groningen Stevens, Gonneke J.W.M. Utrecht University Reijneveld, Sijmen A. University Medical Center Groningen Rommelse, Nanda Radboud University Nijmegen Medical Centre Wijbrand Hoek, H. Parnassia Psychiatric Unit Kretschmer, Tina University of Groningen Bültmann, Ute University Medical Center Groningen

CC - T3 Wave

Wave alternate title	C3, T3
Short description of the wave	The third measurement wave of the TRAILS Clinical cohort included interviews, physical measurements, tasks, registry data, and questionnaires measured among 419 adolescents (34% female), their parents, teachers, and siblings (mean age = 15.9, SD = 0.7).
Type of StudyUnit
Publisher	University Medical Center Groningen
Creators	Ormel, Johan University Medical Center Groningen Verhulst, Frank C. Erasmus MC
Funding information	GB-MW 940-38-011 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Medical Research Council program Funder award URI 100-001-004 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Brainpower Funder award URI 60-60600-97-118 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Risk Behavior and Dependence Funder award URI 261-98-710 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Culture and Health Funder award URI GB-MaGW 480-01-006 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI GB-MaGW 480-07-001 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council medium-sized investment Funder award URI GB-MaGW 452-04-314 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI GB-MaGW 452-06-004 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Social Sciences Council project Funder award URI 636340002 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Cohort Research on Early Detection and Treatment in Mental Health Care Funder award URI 175.010.2003.005 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Large-sized investment Funder award URI 481-08-013 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI 481-11-001 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Longitudinal Survey and Panel Funding Funder award URI 016.130.002 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI 453-16-007/2735 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI Vi.C 191.021 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Vici Funder award URI 024.001.003 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Gravitation Funder award URI EuroSTRESS project FP-006 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Funder award URI ERC-2017-STG-757364 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Funder award URI ERC-CoG-2015-681466 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Funder award URI CP 32 Funder identifier ROR Identifier type URI https://ror.org/ Funder award title Funder award URI
References
(sub) cohort	TRAILS: Clinical cohort
Life stage
Coverage percentage of the measurement for this wave
Start date wave collection	2009-09-01
End date wave collection	2011-02-28
Wave universe description	15.0 - 17.0 years
Stage of measurement
Language	NL
Description of physical data product	Digital files, biomedical samples
Additional info (URL)	https://doi.org/10.17026/dans-2zq-snag
Additional information	The codebooks for the third wave of the clinical cohort in TRAILS can be found via DANS.
Contributors	Oldehinkel, Albertine J. University Medical Center Groningen Hartman, Catharina A. University Medical Center Groningen Rosmalen, Judith G.M. University Medical Center Groningen Veenstra, René University of Groningen Stevens, Gonneke J.W.M. Utrecht University Reijneveld, Sijmen A. University Medical Center Groningen Rommelse, Nanda Radboud University Nijmegen Medical Centre Wijbrand Hoek, H. Parnassia Psychiatric Unit Kretschmer, Tina University of Groningen Bültmann, Ute University Medical Center Groningen

You can also access this dataset using the API (see API Docs).

author	None
author_email	None
creator_user_id	34768773-4537-4d74-8d9d-11e2b32cbbaf
dc_additional_info	In TRAILS, methylation of the Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT) genes was assessed from a blood sample.
dc_analysis_unit	{Individual}
dc_cohort	TRAILS
dc_common_id	0105_CD2
dc_instrument_name	Candidate gene methylation
id	895cf1f6-0cf6-45fa-a637-3434c88b0325
isopen	False
license_title	None
maintainer	None
maintainer_email	None
metadata_created	2024-10-17T12:08:25.916560
metadata_modified	2024-10-20T12:32:47.496335
name	0723d8a48a03ba3b6309fa76ed371d3c
notes	DNA methylation of selected candidate genes, such as Nuclear Receptor Subfamily 3 Group C Member 1 (NR3C1), Solute Carrier Family 6 Member 4 (SLC6A4), and Catechol-O-Methyltransferase (COMT).
num_resources	0
num_tags	0
organization	{'id': '3cea9092-20b7-4a09-85ec-d9b8498cdadc', 'name': 'trails', 'title': 'TRAILS', 'type': 'organization', 'description': "TRAILS (TRacking Adolescents' Individual Lives Survey) is an ongoing, multidisciplinary research on the psychological, social and physical development of adolescents and young adults. More than 2700 participants have participated since they were about eleven years old. For over 20 years, these participants have been examined every 2 to 3 years, through questionnaires, interviews, tests and/or physical measurements. Data was collected not only from participants, but also their family members, teachers, peers, and partners. TRAILS consists of a population cohort (TRAILS: POP) and a clinical cohort (TRAILS: CC). Since 2015, participants’ children have been measured in the offspring study TRAILS NEXT.", 'image_url': 'https://data.individualdevelopment.nl/img/logo_trails.png', 'created': '2024-10-17T13:43:24.736812', 'is_organization': True, 'approval_status': 'approved', 'state': 'active'}
owner_org	3cea9092-20b7-4a09-85ec-d9b8498cdadc
private	False
state	active
title	DNA methylation (candidate genes)
type	measure
cohort	[{'cohort_alternate_title': 'TRAILS: POP', 'cohort_description': 'The TRAILS Population Cohort (TRAILS: POP) started in 2000 (N = 2230 at wave 1) and follows adolescents and young adults from the general population from the age of 11 onwards to study their psychological, social, and physical development. Participants, but also their parents, teachers, peers, and partners, are assessed every 2 to 3 years, through questionnaires, interviews, tests, and physical measurements. Participants were included if they lived in one of the five selected municipalities in Groningen, Friesland and Drenthe (the Netherlands), were born between October 1989 and September 1991, and attended a primary school that agreed to participate at the time.', 'cohort_language': 'NL', 'cohort_purpose': 'During adolescence and young adulthood, people go through profound changes, both physically and psychologically. These changes affect the way they interact with others, and how they process and cope with their experiences. The choices made and directions taken in these phases of life can have a major impact on future well-being, behavior and health, and even affect the next generation. More knowledge of the causes of a favorable or unfavorable development can help to prevent problems or treat them at an early stage. Not only problematic developmental trajectories are of interest, but successful ones as well.', 'cohort_spatial_country_code': 'NL', 'cohort_spatial_geographic_location': 'Groningen,Drenthe,Friesland', 'cohort_time_method': 'Longitudinal.CohortEventBased', 'cohort_title': 'TRAILS: Population cohort', 'cohort_universe': 'Individuals aged 10-30 years old from the North of the Netherlands.', 'cohort_contributor': [{'cohort_contributor': 'Oldehinkel, Albertine J.', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'cohort_contributor_identifier_schemeuri': 'https://orcid.org/', 'cohort_contributor_identifier_type': 'ORCID', 'cohort_contributor_pid': '0000-0003-3925-3913'}, {'cohort_contributor': 'Hartman, Catharina A.', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'cohort_contributor_identifier_schemeuri': 'https://orcid.org/', 'cohort_contributor_identifier_type': 'ORCID', 'cohort_contributor_pid': '0000-0002-8094-8859'}, {'cohort_contributor': 'Rosmalen, Judith G.M.', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Veenstra, René', 'cohort_contributor_affiliation': 'University of Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/012p63287', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Stevens, Gonneke J.W.M. ', 'cohort_contributor_affiliation': 'Utrecht University', 'cohort_contributor_affiliation_identifier': 'https://ror.org/04pp8hn57', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Reijneveld, Sijmen A.', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Rommelse, Nanda', 'cohort_contributor_affiliation': 'Radboud University Nijmegen Medical Centre', 'cohort_contributor_affiliation_identifier': 'https://ror.org/05wg1m734', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Wijbrand Hoek, H.', 'cohort_contributor_affiliation': 'Parnassia Psychiatric Unit', 'cohort_contributor_affiliation_identifier': 'https://ror.org/002wh3v03', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Kretschmer, Tina', 'cohort_contributor_affiliation': 'University of Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/012p63287', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Bültmann, Ute', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}], 'cohort_creator': [{'cohort_creator_affiliation': 'University Medical Center Groningen', 'cohort_creator_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_creator_affiliation_identifier_scheme': 'ROR', 'cohort_creator_affiliation_identifier_schemeuri': 'https://ror.org/', 'cohort_creator_name': 'Ormel, Johan'}, {'cohort_creator_affiliation': 'Erasmus MC', 'cohort_creator_affiliation_identifier': 'https://ror.org/018906e22', 'cohort_creator_affiliation_identifier_scheme': 'ROR', 'cohort_creator_affiliation_identifier_schemeuri': 'https://ror.org/', 'cohort_creator_name': 'Verhulst, Frank C.'}], 'cohort_funding': [{'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Medical Research Council program', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MW 940-38-011'}, {'cohort_funder': 'Netherlands Organisation for Health Research and Development', 'cohort_funder_award_title': 'Brainpower', 'cohort_funder_identifier': 'https://ror.org/01yaj9a77', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '100-001-004'}, {'cohort_funder': 'Netherlands Organisation for Health Research and Development', 'cohort_funder_award_title': 'Risk Behavior and Dependence', 'cohort_funder_identifier': 'https://ror.org/01yaj9a77', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '60-60600-97-118'}, {'cohort_funder': 'Netherlands Organisation for Health Research and Development', 'cohort_funder_award_title': 'Culture and Health', 'cohort_funder_identifier': 'https://ror.org/01yaj9a77', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '261-98-710'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Social Sciences Council medium-sized investment', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MaGW 480-01-006'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Social Sciences Council medium-sized investment', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MaGW 480-07-001'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Social Sciences Council project', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MaGW 452-04-314'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Social Sciences Council project', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MaGW 452-06-004'}, {'cohort_funder': 'Netherlands Organisation for Health Research and Development', 'cohort_funder_award_title': 'Longitudinal Cohort Research on Early Detection and Treatment in Mental Health Care', 'cohort_funder_identifier': 'https://ror.org/01yaj9a77', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '636340002'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Large-sized investment', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '175.010.2003.005'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Longitudinal Survey and Panel Funding ', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '481-08-013'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Longitudinal Survey and Panel Funding ', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '481-11-001'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Vici', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '016.130.002'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Vici', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '453-16-007/2735'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Vici', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'Vi.C 191.021'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Gravitation', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '024.001.003'}, {'cohort_funder': 'European Science Foundation ', 'cohort_funder_identifier': 'https://ror.org/04esata81', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'EuroSTRESS project FP-006'}, {'cohort_funder': 'European Research Council ', 'cohort_funder_identifier': 'https://ror.org/0472cxd90', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'ERC-2017-STG-757364 '}, {'cohort_funder': 'European Research Council ', 'cohort_funder_identifier': 'https://ror.org/0472cxd90', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'ERC-CoG-2015-681466'}, {'cohort_funder': 'Biobanking and BioMolecular resources Research Infrastructure The Netherlands', 'cohort_funder_identifier': 'https://ror.org/0003kpv33', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'CP 32'}], 'cohort_publisher': [{'cohort_publisher_identifier': 'https://ror.org/03cv38k47', 'cohort_publisher_identifier_type': 'ROR', 'cohort_publisher_name': 'University Medical Center Groningen'}], 'cohort_references': [{'cohort_reference_citation': 'Oldehinkel AJ, Rosmalen JGM, Buitelaar JK, Hoek HW, Ormel J, Raven D, Reijneveld SA, Veenstra R, Verhulst FC, Vollebergh WAM, Hartman CA. Cohort Profile update. The TRacking Adolescents’ Individual Lives Survey (TRAILS)[1]. Int J Epidemiol 2015; 44(1):76-76n.', 'cohort_reference_identifier': 'https://doi.org/10.1093/ije/dyu225', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'Huisman M, Oldehinkel AJ, De Winter AF, Minderaa RB, De Bildt A, Huizink AC, Verhulst FC, Ormel J. Cohort profile: The Dutch “TRacking Adolescents’ Individual Lives’ Survey”; TRAILS. Int J Epidemiol 2008; 37: 1227-35. ', 'cohort_reference_identifier': 'https://doi.org/10.1093/ije/dym273', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'De Winter AF, Oldehinkel AJ, Veenstra R, Brunnekreef JA, Verhulst FC, Ormel J. Evaluation of nonresponse bias in mental health determinants and outcomes in a large sample of preadolescents. Eur J Epidemiol 2005; 20:173-81.', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-004-4948-6', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'Nederhof E, Jörg, F, Raven D, Veenstra R, Verhulst FC, Ormel J, Oldehinkel AJ. Benefits of extensive recruitment effort persist during follow-ups and are constant across age and survey method. The TRAILS study. BMC Med Res Methodol 2012; 12:93', 'cohort_reference_identifier': 'https://doi.org/10.1186/1471-2288-12-93', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': "Ormel J, Oldehinkel AJ, Sijtsema J, van Oort F, Raven D, Veenstra R, Vollebergh WA, Verhulst FC. The TRacking Adolescents' Individual Lives Survey (TRAILS): design, current status, and selected findings. J Am Acad Child Adolesc Psychiatry 2012; 51(10):1020-36.", 'cohort_reference_identifier': 'https://doi.org/10.1016/j.jaac.2012.08.004', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}]}, {'cohort_alternate_title': 'TRAILS: CC', 'cohort_description': 'The TRAILS Population Cohort (TRAILS: POP) started in 2000 (N = 2230 at wave 1) and follows adolescents and young adults from the general population from the age of 11 onwards to study their psychological, social, and physical development. Participants, but also their parents, teachers, peers, and partners, are assessed every 2 to 3 years, through questionnaires, interviews, tests, and physical measurements. Participants were included if they lived in one of the five selected municipalities in Groningen, Friesland and Drenthe (the Netherlands), were born between October 1989 and September 1991, and attended a primary school that agreed to participate at the time.', 'cohort_language': 'NL', 'cohort_purpose': 'During adolescence and young adulthood, people go through profound changes, both physically and psychologically. These changes affect the way they interact with others, and how they process and cope with their experiences. The choices made and directions taken in these phases of life can have a major impact on future well-being, behavior and health, and even affect the next generation. More knowledge of the causes of a favorable or unfavorable development can help to prevent problems or treat them at an early stage. Not only problematic developmental trajectories are of interest, but successful ones as well.', 'cohort_spatial_country_code': 'NL', 'cohort_spatial_geographic_location': 'Groningen,Drenthe,Friesland', 'cohort_time_method': 'Longitudinal.CohortEventBased', 'cohort_title': 'TRAILS: Clinical cohort', 'cohort_universe': 'Individuals aged 10-30 years referred to psychiatric outpatient clinics before the age of 11 in the Northern Netherlands.', 'cohort_contributor': [{'cohort_contributor': 'Oldehinkel, Albertine J.', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'cohort_contributor_identifier_schemeuri': 'https://orcid.org/', 'cohort_contributor_identifier_type': 'ORCID', 'cohort_contributor_pid': '0000-0003-3925-3913'}, {'cohort_contributor': 'Hartman, Catharina A.', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'cohort_contributor_identifier_schemeuri': 'https://orcid.org/', 'cohort_contributor_identifier_type': 'ORCID', 'cohort_contributor_pid': '0000-0002-8094-8859'}, {'cohort_contributor': 'Rosmalen, Judith G.M.', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Veenstra, René', 'cohort_contributor_affiliation': 'University of Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/012p63287', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Stevens, Gonneke J.W.M. ', 'cohort_contributor_affiliation': 'Utrecht University', 'cohort_contributor_affiliation_identifier': 'https://ror.org/04pp8hn57', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Reijneveld, Sijmen A.', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Rommelse, Nanda', 'cohort_contributor_affiliation': 'Radboud University Nijmegen Medical Centre', 'cohort_contributor_affiliation_identifier': 'https://ror.org/05wg1m734', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Wijbrand Hoek, H.', 'cohort_contributor_affiliation': 'Parnassia Psychiatric Unit', 'cohort_contributor_affiliation_identifier': 'https://ror.org/002wh3v03', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Kretschmer, Tina', 'cohort_contributor_affiliation': 'University of Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/012p63287', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}, {'cohort_contributor': 'Bültmann, Ute', 'cohort_contributor_affiliation': 'University Medical Center Groningen', 'cohort_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_contributor_affiliation_identifier_scheme': 'ROR', 'cohort_contributor_affiliation_identifier_schemeuri': 'https://ror.org/'}], 'cohort_creator': [{'cohort_creator_affiliation': 'University Medical Center Groningen', 'cohort_creator_affiliation_identifier': 'https://ror.org/03cv38k47', 'cohort_creator_affiliation_identifier_scheme': 'ROR', 'cohort_creator_affiliation_identifier_schemeuri': 'https://ror.org/', 'cohort_creator_name': 'Ormel, Johan'}, {'cohort_creator_affiliation': 'Erasmus MC', 'cohort_creator_affiliation_identifier': 'https://ror.org/018906e22', 'cohort_creator_affiliation_identifier_scheme': 'ROR', 'cohort_creator_affiliation_identifier_schemeuri': 'https://ror.org/', 'cohort_creator_name': 'Verhulst, Frank C.'}], 'cohort_funding': [{'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Medical Research Council program', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MW 940-38-011'}, {'cohort_funder': 'Netherlands Organisation for Health Research and Development', 'cohort_funder_award_title': 'Brainpower', 'cohort_funder_identifier': 'https://ror.org/01yaj9a77', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '100-001-004'}, {'cohort_funder': 'Netherlands Organisation for Health Research and Development', 'cohort_funder_award_title': 'Risk Behavior and Dependence', 'cohort_funder_identifier': 'https://ror.org/01yaj9a77', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '60-60600-97-118'}, {'cohort_funder': 'Netherlands Organisation for Health Research and Development', 'cohort_funder_award_title': 'Culture and Health', 'cohort_funder_identifier': 'https://ror.org/01yaj9a77', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '261-98-710'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Social Sciences Council medium-sized investment', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MaGW 480-01-006'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Social Sciences Council medium-sized investment', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MaGW 480-07-001'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Social Sciences Council project', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MaGW 452-04-314'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Social Sciences Council project', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'GB-MaGW 452-06-004'}, {'cohort_funder': 'Netherlands Organisation for Health Research and Development', 'cohort_funder_award_title': 'Longitudinal Cohort Research on Early Detection and Treatment in Mental Health Care', 'cohort_funder_identifier': 'https://ror.org/01yaj9a77', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '636340002'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Large-sized investment', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '175.010.2003.005'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Longitudinal Survey and Panel Funding ', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '481-08-013'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Longitudinal Survey and Panel Funding ', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '481-11-001'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Vici', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '016.130.002'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Vici', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '453-16-007/2735'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Vici', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'Vi.C 191.021'}, {'cohort_funder': 'Dutch Research Council', 'cohort_funder_award_title': 'Gravitation', 'cohort_funder_identifier': 'https://ror.org/04jsz6e67', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': '024.001.003'}, {'cohort_funder': 'European Science Foundation ', 'cohort_funder_identifier': 'https://ror.org/04esata81', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'EuroSTRESS project FP-006'}, {'cohort_funder': 'European Research Council ', 'cohort_funder_identifier': 'https://ror.org/0472cxd90', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'ERC-2017-STG-757364 '}, {'cohort_funder': 'European Research Council ', 'cohort_funder_identifier': 'https://ror.org/0472cxd90', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'ERC-CoG-2015-681466'}, {'cohort_funder': 'Biobanking and BioMolecular resources Research Infrastructure The Netherlands', 'cohort_funder_identifier': 'https://ror.org/0003kpv33', 'cohort_funder_identifier_schemuri': 'https://ror.org/', 'cohort_funder_identifier_type': 'ROR', 'cohort_grant_number': 'CP 32'}], 'cohort_publisher': [{'cohort_publisher_identifier': 'https://ror.org/03cv38k47', 'cohort_publisher_identifier_type': 'ROR', 'cohort_publisher_name': 'University Medical Center Groningen'}], 'cohort_references': [{'cohort_reference_citation': 'Oldehinkel AJ, Rosmalen JGM, Buitelaar JK, Hoek HW, Ormel J, Raven D, Reijneveld SA, Veenstra R, Verhulst FC, Vollebergh WAM, Hartman CA. Cohort Profile update. The TRacking Adolescents’ Individual Lives Survey (TRAILS)[1]. Int J Epidemiol 2015; 44(1):76-76n.', 'cohort_reference_identifier': 'https://doi.org/10.1093/ije/dyu225', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'Huisman M, Oldehinkel AJ, De Winter AF, Minderaa RB, De Bildt A, Huizink AC, Verhulst FC, Ormel J. Cohort profile: The Dutch “TRacking Adolescents’ Individual Lives’ Survey”; TRAILS. Int J Epidemiol 2008; 37: 1227-35. ', 'cohort_reference_identifier': 'https://doi.org/10.1093/ije/dym273', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'De Winter AF, Oldehinkel AJ, Veenstra R, Brunnekreef JA, Verhulst FC, Ormel J. Evaluation of nonresponse bias in mental health determinants and outcomes in a large sample of preadolescents. Eur J Epidemiol 2005; 20:173-81.', 'cohort_reference_identifier': 'https://doi.org/10.1007/s10654-004-4948-6', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': 'Nederhof E, Jörg, F, Raven D, Veenstra R, Verhulst FC, Ormel J, Oldehinkel AJ. Benefits of extensive recruitment effort persist during follow-ups and are constant across age and survey method. The TRAILS study. BMC Med Res Methodol 2012; 12:93', 'cohort_reference_identifier': 'https://doi.org/10.1186/1471-2288-12-93', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}, {'cohort_reference_citation': "Ormel J, Oldehinkel AJ, Sijtsema J, van Oort F, Raven D, Veenstra R, Vollebergh WA, Verhulst FC. The TRacking Adolescents' Individual Lives Survey (TRAILS): design, current status, and selected findings. J Am Acad Child Adolesc Psychiatry 2012; 51(10):1020-36.", 'cohort_reference_identifier': 'https://doi.org/10.1016/j.jaac.2012.08.004', 'cohort_reference_identifier_type': 'DOI', 'cohort_reference_type': 'IsDescribedBy'}]}]
dc_DOI	[{'dc_identifier_type': 'DOI', 'dc_pid': '10.60641/7hea-wc29'}]
dc_constructs	[{'dc_construct': 'physiology'}]
dc_labels	[{'dc_label': 'omics'}, {'dc_label': 'genomics'}, {'dc_label': 'epigenetics'}, {'dc_label': 'dna'}, {'dc_label': 'catecholamine'}, {'dc_label': 'glucocorticoid receptor gene'}, {'dc_label': 'serotonin transporter gene'}]
dc_modes_of_collection	[{'dc_mode_of_collection': 'MeasurementsAndTests'}]
dc_modes_of_collection_sub	[{'dc_mode_of_collection_sub': 'Biological sample/measurement'}]
measure_age_range	[{'measure_age_month': 180}, {'measure_age_month': 181}, {'measure_age_month': 182}, {'measure_age_month': 183}, {'measure_age_month': 184}, {'measure_age_month': 185}, {'measure_age_month': 186}, {'measure_age_month': 187}, {'measure_age_month': 188}, {'measure_age_month': 189}, {'measure_age_month': 190}, {'measure_age_month': 191}, {'measure_age_month': 192}, {'measure_age_month': 193}, {'measure_age_month': 194}, {'measure_age_month': 195}, {'measure_age_month': 196}, {'measure_age_month': 197}, {'measure_age_month': 198}, {'measure_age_month': 199}, {'measure_age_month': 200}, {'measure_age_month': 201}, {'measure_age_month': 202}, {'measure_age_month': 203}, {'measure_age_month': 204}]
study	[{'study_alternate_title': 'TRAILS', 'study_language': 'NL', 'study_purpose': 'The overall purpose of TRAILS is to contribute to the understanding of the determinants of adolescents’ mental (ill-)health and social development during adolescence and young adulthood, as well as the mechanisms underlying the associations between determinants and outcomes.', 'study_time_method': 'Longitudinal', 'study_universe': 'Adolescents, young adults, and adults from the general population (Population cohort) as well as with a high-risk profile (Clinical cohort), and their offspring (The Next Generation), selected from urban and rural areas in the North of the Netherlands at the time of the baseline assessment. The largest ethnic group is the Dutch (89.7%).\n\n', 'title': "TRacking Adolescents' Individual Lives Survey", 'study_contact': [{'study_contact_affiliation': 'University Medical Center Groningen', 'study_contact_mail': 'a.j.oldehinkel@umcg.nl', 'study_contact_name': 'Oldehinkel, Albertine J.'}, {'study_contact_affiliation': 'University Medical Center Groningen', 'study_contact_mail': 'c.a.hartman@umcg.nl', 'study_contact_name': 'Hartman, Catharina A.'}], 'study_contributor': [{'study_contributor_affiliation': 'University Medical Center Groningen', 'study_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_identifier_schemeuri': 'https://orcid.org/', 'study_contributor_identifier_type': 'ORCID', 'study_contributor_name': 'Oldehinkel, Albertine J.', 'study_contributor_pid': '0000-0003-3925-3913'}, {'study_contributor_affiliation': 'University Medical Center Groningen', 'study_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_identifier_schemeuri': 'https://orcid.org/', 'study_contributor_identifier_type': 'ORCID', 'study_contributor_name': 'Hartman, Catharina A.', 'study_contributor_pid': '0000-0002-8094-8859'}, {'study_contributor_affiliation': 'University Medical Center Groningen', 'study_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_name': 'Rosmalen, Judith G.M.'}, {'study_contributor_affiliation': 'University of Groningen', 'study_contributor_affiliation_identifier': 'https://ror.org/012p63287', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_name': 'Veenstra, René'}, {'study_contributor_affiliation': 'Utrecht University', 'study_contributor_affiliation_identifier': 'https://ror.org/04pp8hn57', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_name': 'Stevens, Gonneke J.W.M. '}, {'study_contributor_affiliation': 'University Medical Center Groningen', 'study_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_name': 'Reijneveld, Sijmen A.'}, {'study_contributor_affiliation': 'Radboud University Nijmegen Medical Centre', 'study_contributor_affiliation_identifier': 'https://ror.org/05wg1m734', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_name': 'Rommelse, Nanda'}, {'study_contributor_affiliation': 'Parnassia Psychiatric Unit', 'study_contributor_affiliation_identifier': 'https://ror.org/002wh3v03', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_name': 'Wijbrand Hoek, H.'}, {'study_contributor_affiliation': 'University of Groningen', 'study_contributor_affiliation_identifier': 'https://ror.org/012p63287', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_name': 'Kretschmer, Tina'}, {'study_contributor_affiliation': 'University Medical Center Groningen', 'study_contributor_affiliation_identifier': 'https://ror.org/03cv38k47', 'study_contributor_affiliation_identifier_scheme': 'ROR', 'study_contributor_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_contributor_name': 'Bültmann, Ute'}], 'study_data_access': [{'study_data_access_URL': 'https://www.trails.nl/en/hoofdmenu/data/data-use', 'study_data_access_description': 'A description of how to access TRAILS data can be found on the TRAILS website. Data are released after each assessment wave under specified conditions.'}], 'study_funding': [{'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Medical Research Council program', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'GB-MW 940-38-011'}, {'study_funder': 'Netherlands Organisation for Health Research and Development', 'study_funder_award_title': 'Brainpower', 'study_funder_identifier': 'https://ror.org/01yaj9a77', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '100-001-004'}, {'study_funder': 'Netherlands Organisation for Health Research and Development', 'study_funder_award_title': 'Risk Behavior and Dependence', 'study_funder_identifier': 'https://ror.org/01yaj9a77', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '60-60600-97-118'}, {'study_funder': 'Netherlands Organisation for Health Research and Development', 'study_funder_award_title': 'Culture and Health', 'study_funder_identifier': 'https://ror.org/01yaj9a77', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '261-98-710'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Social Sciences Council medium-sized investment', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'GB-MaGW 480-01-006'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Social Sciences Council medium-sized investment', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'GB-MaGW 480-07-001'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Social Sciences Council project', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'GB-MaGW 452-04-314'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Social Sciences Council project', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'GB-MaGW 452-06-004'}, {'study_funder': 'Netherlands Organisation for Health Research and Development', 'study_funder_award_title': 'Longitudinal Cohort Research on Early Detection and Treatment in Mental Health Care', 'study_funder_identifier': 'https://ror.org/01yaj9a77', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '636340002'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Large-sized investment', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '175.010.2003.005'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Longitudinal Survey and Panel Funding ', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '481-08-013'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Longitudinal Survey and Panel Funding ', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '481-11-001'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Vici', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '016.130.002'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Vici', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '453-16-007/2735'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Vici', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'Vi.C 191.021'}, {'study_funder': 'Dutch Research Council', 'study_funder_award_title': 'Gravitation', 'study_funder_identifier': 'https://ror.org/04jsz6e67', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': '024.001.003'}, {'study_funder': 'European Science Foundation ', 'study_funder_identifier': 'https://ror.org/04esata81', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'EuroSTRESS project FP-006'}, {'study_funder': 'European Research Council ', 'study_funder_identifier': 'https://ror.org/0472cxd90', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'ERC-2017-STG-757364 '}, {'study_funder': 'European Research Council ', 'study_funder_identifier': 'https://ror.org/0472cxd90', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'ERC-CoG-2015-681466'}, {'study_funder': 'Biobanking and BioMolecular resources Research Infrastructure The Netherlands', 'study_funder_identifier': 'https://ror.org/0003kpv33', 'study_funder_identifier_schemuri': 'https://ror.org/', 'study_funder_identifier_type': 'ROR', 'study_grant_number': 'CP 32'}], 'study_principal_investigators': [{'study_pi_affiliation': 'University Medical Center Groningen', 'study_pi_affiliation_identifier': 'https://ror.org/03cv38k47', 'study_pi_affiliation_identifier_scheme': 'ROR', 'study_pi_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_pi_name': 'Ormel, Johan'}, {'study_pi_affiliation': 'Erasmus MC', 'study_pi_affiliation_identifier': 'https://ror.org/018906e22', 'study_pi_affiliation_identifier_scheme': 'ROR', 'study_pi_affiliation_identifier_schemeuri': 'https://ror.org/', 'study_pi_name': 'Verhulst, Frank C.'}], 'study_publisher': [{'study_publisher_identifier': 'https://ror.org/03cv38k47', 'study_publisher_identifier_schemeuri': 'https://ror.org/', 'study_publisher_identifier_type': 'ROR', 'study_publisher_name': 'University Medical Center Groningen'}], 'study_references': [{'study_reference_citation': 'Oldehinkel AJ, Rosmalen JGM, Buitelaar JK, Hoek HW, Ormel J, Raven D, Reijneveld SA, Veenstra R, Verhulst FC, Vollebergh WAM, Hartman CA. 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Int J Epidemiol 2022.', 'study_reference_identifier': 'https://doi.org/10.1093/ije/dyac066', 'study_reference_identifier_type': 'DOI', 'study_reference_type': 'IsDescribedBy'}, {'study_reference_citation': 'De Winter AF, Oldehinkel AJ, Veenstra R, Brunnekreef JA, Verhulst FC, Ormel J. Evaluation of nonresponse bias in mental health determinants and outcomes in a large sample of preadolescents. Eur J Epidemiol 2005; 20:173-81.', 'study_reference_identifier': 'https://doi.org/10.1007/s10654-004-4948-6', 'study_reference_identifier_type': 'DOI', 'study_reference_type': 'IsDescribedBy'}, {'study_reference_citation': 'Nederhof E, Jörg, F, Raven D, Veenstra R, Verhulst FC, Ormel J, Oldehinkel AJ. Benefits of extensive recruitment effort persist during follow-ups and are constant across age and survey method. The TRAILS study. BMC Med Res Methodol 2012; 12:93', 'study_reference_identifier': 'https://doi.org/10.1186/1471-2288-12-93', 'study_reference_identifier_type': 'DOI', 'study_reference_type': 'IsDescribedBy'}, {'study_reference_citation': "Ormel J, Oldehinkel AJ, Sijtsema J, van Oort F, Raven D, Veenstra R, Vollebergh WA, Verhulst FC. The TRacking Adolescents' Individual Lives Survey (TRAILS): design, current status, and selected findings. J Am Acad Child Adolesc Psychiatry 2012; 51(10):1020-36.", 'study_reference_identifier': 'https://doi.org/10.1016/j.jaac.2012.08.004', 'study_reference_identifier_type': 'DOI', 'study_reference_type': 'IsDescribedBy'}]}]
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